Reactome | Tgfbr1 [plasma membrane]

Tgfbr1 [plasma membrane]

Stable Identifier

R-MMU-170839

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

TGFBR1, Q64729

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Deubiquitination (Mus musculus)
    - Ub-specific processing proteases (Mus musculus)
      - USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Mus musculus)
        
        USP15:SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1 [cytosol] (Mus musculus)
        
        SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1 [cytosol] (Mus musculus)
        
        SMAD7:SMURF2:TGFBR1 [plasma membrane] (Mus musculus)
        
        Tgfbr1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q64729

Gene Names

Tgfbr1

Reference Genes

BioGPS Gene:21812 Tgfbr1

ENSEMBL:ENSMUSG00000007613

KEGG Gene (Mus musculus):21812 Tgfbr1

Monarch:21812 Tgfbr1

NCBI Gene:21812 Tgfbr1

UCSC:Q64729 Tgfbr1

Reference Transcript

Other Identifiers

10504817

106644_at

1420893_a_at

1420894_at

1420895_at

17413915

21812

4431045

4455593

4519309

4710787

4890052

4905530

4908316

5367563

5458612

5476760

5579347

5603436

92427_at

A_51_P280137

A_52_P4538

A_55_P2137206

A_55_P2137211

GE33803

GO:0000003

GO:0000166

GO:0000186

GO:0001501

GO:0001525

GO:0001701

GO:0001822

GO:0001824

GO:0001837

GO:0001937

GO:0001938

GO:0002088

GO:0002376

GO:0003222

GO:0003223

GO:0003674

GO:0004672

GO:0004674

GO:0004675

GO:0005024

GO:0005025

GO:0005102

GO:0005114

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005768

GO:0005886

GO:0005901

GO:0005923

GO:0006355

GO:0006464

GO:0006468

GO:0006915

GO:0007010

GO:0007165

GO:0007178

GO:0007179

GO:0007399

GO:0007507

GO:0008150

GO:0008219

GO:0008283

GO:0008284

GO:0008354

GO:0008584

GO:0009058

GO:0009790

GO:0009791

GO:0009952

GO:0009986

GO:0010468

GO:0010628

GO:0010717

GO:0010718

GO:0010862

GO:0016020

GO:0016021

GO:0016301

GO:0016310

GO:0016323

GO:0016324

GO:0016361

GO:0016740

GO:0018105

GO:0018107

GO:0019838

GO:0019899

GO:0022607

GO:0030054

GO:0030154

GO:0030198

GO:0030199

GO:0030307

GO:0030335

GO:0031396

GO:0031410

GO:0031625

GO:0032331

GO:0032924

GO:0032991

GO:0034330

GO:0034641

GO:0035556

GO:0040007

GO:0040008

GO:0040011

GO:0042118

GO:0043065

GO:0043066

GO:0043167

GO:0043226

GO:0043235

GO:0043393

GO:0043542

GO:0043627

GO:0044877

GO:0045121

GO:0045602

GO:0045893

GO:0046332

GO:0046777

GO:0046872

GO:0048179

GO:0048185

GO:0048538

GO:0048646

GO:0048663

GO:0048701

GO:0048705

GO:0048762

GO:0048844

GO:0048856

GO:0048870

GO:0050431

GO:0051272

GO:0051491

GO:0051496

GO:0051897

GO:0060017

GO:0060021

GO:0060037

GO:0060043

GO:0060317

GO:0060389

GO:0060391

GO:0060412

GO:0060978

GO:0060982

GO:0070411

GO:0070723

GO:0071363

GO:0071560

GO:1902894

GO:1902895

GO:1905007

GO:1905075

GO:1905223

GO:2001235

GO:2001237

ILMN_1214505

ILMN_2602711

ILMN_2708965

ILMN_2708966

ILMN_2980532

d25540_s_at

mMC015662

mMC019469

mMR031099

Participates

as a component of

Other forms of this molecule

Tgfbr1 [plasma membrane]

phospho-Tgfbr1 [plasma membrane]

Inferred From

TGFBR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001299797.1, NP_001299798.1, NP_033396.1

ZINC - Substances

TGFR1_MOUSE

ZINC target

Q64729

Ensembl

ENSMUST00000007757, ENSMUSP00000007757, ENSMUSP00000048501, ENSMUSG00000007613, ENSMUST00000044234

PRO

Q64729

GlyGen

Q64729

MGI

98728

ZINC - Predictions - Purchasable

TGFR1_MOUSE

HMDB Protein

HMDBP14494

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62312	2	Tgfbr2 [plasma membrane] (R-MMU-4332222) Tgfbr2 [plasma membrane] (R-MMU-170842)	0.667	3
UniProt:P84022 SMAD3	20	Ub-SMAD3 [cytosol] (R-HSA-6782830) p-S423,S425-SMAD3 D258N [cytosol] (R-HSA-3315470) p-S423,S425-SMAD3 R268C [cytosol] (R-HSA-3315075) p-S423,S425-SMAD3 R268H [cytosol] (R-HSA-3315080) SMAD3 Q316* [cytosol] (R-HSA-9668765) SMAD3 Y384* [cytosol] (R-HSA-9668782) SMAD3 W326* [cytosol] (R-HSA-9668766) SMAD3 E246* [cytosol] (R-HSA-9668776) SMAD3 Q358* [cytosol] (R-HSA-9668772) SMAD3 Q322* [cytosol] (R-HSA-9668773) SMAD3 S425F [cytosol] (R-HSA-8944158) SMAD3 E383* [cytosol] (R-HSA-9668775) SMAD3 R368* [cytosol] (R-HSA-9668768) SMAD3 Y298* [cytosol] (R-HSA-9668769) SMAD3 S425C [cytosol] (R-HSA-3308499) SMAD3 [nucleoplasm] (R-HSA-206150) 2xADPRib-p-S423,S425-SMAD3 [nucleoplasm] (R-HSA-2187326) p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-2176471) SMAD3 [cytosol] (R-HSA-170855) p-S423,S425-SMAD3 [cytosol] (R-HSA-171184)	0.576	6
UniProt:P49817 Cav1	6	caveolin-1 [lipid droplet] (R-MMU-163603) Cav1 [endocytic vesicle membrane] (R-MMU-535009) Cav1 [lipid droplet] (R-MMU-163510) Cav1 [Golgi membrane] (R-MMU-204504) Cav1 [early endosome membrane] (R-MMU-5368451) Cav1 [plasma membrane] (R-MMU-534994)	0.558	4
UniProt:P15379	2	Cd44 [secretory granule membrane] (R-MMU-6804776) Cd44 [plasma membrane] (R-MMU-1031688)	0.518	4