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phosphorylated anaphase promoting complex (APC/C) [cytosol]
Stable Identifier
R-MMU-174191
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
Mitotic Spindle Checkpoint (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Regulation of mitotic cell cycle (Mus musculus)
APC/C-mediated degradation of cell cycle proteins (Mus musculus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Mus musculus)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Degradation of multiubiquitinated cell cycle proteins (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of Cyclin B (Mus musculus)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Degradation of multiubiquitinated Cyclin B (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
APC/C:Cdc20 mediated degradation of Securin (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Mus musculus)
APC-Cdc20 mediated degradation of Nek2A (Mus musculus)
Association of Nek2A with MCC:APC/C (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Degradation of multiubiquitinated Nek2A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Multiubiquitination of Nek2A (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Mus musculus)
Association of Cyclin A with the APC/C (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Mus musculus)
Association of Cdh1 with the APC/C (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Dissociation of Cdc20 from APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
S Phase (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
DNA Replication (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Anapc1 [cytosol]
(Mus musculus)
Anapc10 [cytosol]
(Mus musculus)
ANAPC11 [cytosol]
(Mus musculus)
Anapc15 [cytosol]
(Mus musculus)
Anapc16 [cytosol]
(Mus musculus)
Anapc2 [cytosol]
(Mus musculus)
Anapc4 [cytosol]
(Mus musculus)
Anapc5 [cytosol]
(Mus musculus)
Anapc7 [cytosol]
(Mus musculus)
Cdc16 [cytosol]
(Mus musculus)
Cdc23 [cytosol]
(Mus musculus)
Cdc26 [cytosol]
(Mus musculus)
Cdc27 [cytosol]
(Mus musculus)
Ube2c [cytosol]
(Mus musculus)
Ube2d1 [cytosol]
(Mus musculus)
Ube2e1 [cytosol]
(Mus musculus)
Ube2s [cytosol]
(Mus musculus)
Participates
as an input of
Association of Cdh1 with the APC/C (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
as an output of
Dissociation of Cdc20 from APC/C complex (Mus musculus)
as a component of
CDC20:p-APC/C [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Inferred From
phosphorylated anaphase promoting complex (APC/C) [cytosol]
(Homo sapiens)
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