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Ube2c [cytosol]
Stable Identifier
R-MMU-174244
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
UBE2C, Q9D1C1
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
Mitotic Spindle Checkpoint (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Regulation of mitotic cell cycle (Mus musculus)
APC/C-mediated degradation of cell cycle proteins (Mus musculus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Mus musculus)
APC/C:Cdh1 polyubiquitinates SKP2 (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Mus musculus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Degradation of multiubiquitinated cell cycle proteins (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of Cyclin B (Mus musculus)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Degradation of multiubiquitinated Cyclin B (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
APC/C:Cdc20 mediated degradation of Securin (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Mus musculus)
APC-Cdc20 mediated degradation of Nek2A (Mus musculus)
Association of Nek2A with MCC:APC/C (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Degradation of multiubiquitinated Nek2A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Multiubiquitination of Nek2A (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Mus musculus)
Association of Cyclin A with the APC/C (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Mus musculus)
Association of Cdh1 with the APC/C (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Dissociation of Cdc20 from APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
S Phase (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
DNA Replication (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen processing: Ubiquitination & Proteasome degradation (Mus musculus)
Interaction of E3 with substrate and E2-Ub complex (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Polyubiquitination of substrate (Mus musculus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Transfer of ubiquitin from E1 to E2 (Mus musculus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Mus musculus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Protein ubiquitination (Mus musculus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Mus musculus)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Mus musculus)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Mus musculus)
Ube2c [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9D1C1
Gene Names
Ube2c
Reference Genes
BioGPS Gene:68612 Ube2c
ENSEMBL:ENSMUSG00000001403
ENSEMBL:ENSMUSG00000001403.14 Ube2c
KEGG Gene (Mus musculus):68612 Ube2c
Monarch:68612 Ube2c
NCBI Gene:68612 Ube2c
UCSC:Q9D1C1 Ube2c
Reference Transcript
RefSeq:NM_026785.2 Ube2c
Other Identifiers
10478572
1452954_at
17379523
4405341
4547545
4885983
4979024
5037049
5080722
5132943
5180613
5480512
5554245
68612
A_51_P451151
A_55_P1996941
GE38444
GO:0000151
GO:0000166
GO:0000209
GO:0000278
GO:0003824
GO:0004842
GO:0005524
GO:0005634
GO:0005680
GO:0005829
GO:0005886
GO:0006511
GO:0007049
GO:0007059
GO:0010458
GO:0010994
GO:0016567
GO:0016740
GO:0019538
GO:0030071
GO:0030163
GO:0031145
GO:0031536
GO:0036211
GO:0043226
GO:0044389
GO:0045842
GO:0051301
GO:0061631
GO:0065003
GO:0070936
GO:0070979
GO:0140014
GO:0140096
ILMN_1229321
aa268341_s_at
mMC021592
Participates
as a member of
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Mus musculus)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Mus musculus)
as a candidate of
E2 Ubiquitin-conjugating enzyme [cytosol] (Mus musculus)
as a component of
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Other forms of this molecule
Ube2c [cytosol]
Ube2c [nucleoplasm]
Ube2c [nucleoplasm]
Inferred From
UBE2C [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_081061.1
IntEnz
2.3.2.23
,
2.3.2.24
Ensembl
ENSMUSP00000085581
,
ENSMUST00000088248
,
ENSMUSG00000001403
PRO
Q9D1C1
MGI
1915862
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