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Cdkn1a [nucleoplasm]
Stable Identifier
R-MMU-182585
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
CDKN1A, P39689
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G1/S DNA Damage Checkpoints (Mus musculus)
p53-Dependent G1/S DNA damage checkpoint (Mus musculus)
p53-Dependent G1 DNA Damage Response (Mus musculus)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Mitotic G1 phase and G1/S transition (Mus musculus)
G1 Phase (Mus musculus)
Cyclin D associated events in G1 (Mus musculus)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Mus musculus)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Mus musculus)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Mus musculus)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
G1/S Transition (Mus musculus)
Cyclin E associated events during G1/S transition (Mus musculus)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
SCF(Skp2)-mediated degradation of p27/p21 (Mus musculus)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Mus musculus)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Translocation of p21 to the nucleus (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
S Phase (Mus musculus)
Cyclin A:Cdk2-associated events at S phase entry (Mus musculus)
Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Mus musculus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
SCF(Skp2)-mediated degradation of p27/p21 (Mus musculus)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Mus musculus)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Translocation of p21 to the nucleus (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular Senescence (Mus musculus)
DNA Damage/Telomere Stress Induced Senescence (Mus musculus)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Senescence-Associated Secretory Phenotype (SASP) (Mus musculus)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Mus musculus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Mus musculus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Developmental Biology (Mus musculus)
Transcriptional regulation of granulopoiesis (Mus musculus)
CEBPA binds CDKN1A (p21) (Mus musculus)
CEBPA:CDKN1A [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Transcription of Cell Cycle Genes (Mus musculus)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Mus musculus)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Cdkn1a [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P39689
Gene Names
Cdkn1a
Reference Genes
BioGPS Gene:12575 Cdkn1a
ENSEMBL:ENSMUSG00000023067
ENSEMBL:ENSMUSG00000023067.15 Cdkn1a
KEGG Gene (Mus musculus):12575 Cdkn1a
Monarch:12575 Cdkn1a
NCBI Gene:12575 Cdkn1a
UCSC:P39689 Cdkn1a
Reference Transcript
RefSeq:NM_001111099.2 Cdkn1a
RefSeq:NM_007669.5 Cdkn1a
Other Identifiers
10443463
12575
1421679_a_at
1424638_at
17335467
4335093
4698898
4885748
5132035
5208707
5517298
5530406
5574622
5601184
94881_at
98067_at
A_51_P363947
A_55_P1976204
A_55_P1986282
GE33491
GO:0000278
GO:0000307
GO:0001701
GO:0001933
GO:0001934
GO:0002376
GO:0003824
GO:0004860
GO:0004861
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0006606
GO:0006886
GO:0006913
GO:0006974
GO:0006977
GO:0006978
GO:0007049
GO:0007095
GO:0007265
GO:0007346
GO:0007507
GO:0008285
GO:0008544
GO:0009411
GO:0010389
GO:0010629
GO:0012501
GO:0016604
GO:0016740
GO:0019901
GO:0019912
GO:0023052
GO:0030154
GO:0030216
GO:0030308
GO:0030332
GO:0030890
GO:0031625
GO:0031668
GO:0032991
GO:0034198
GO:0036211
GO:0042060
GO:0042246
GO:0042326
GO:0042771
GO:0043066
GO:0043068
GO:0043226
GO:0043616
GO:0044877
GO:0046872
GO:0048144
GO:0048146
GO:0048471
GO:0048856
GO:0051726
GO:0070557
GO:0071479
GO:0071480
GO:0071493
GO:0072331
GO:0090398
GO:0090399
GO:0090402
GO:0098772
GO:0140096
GO:0140311
GO:0140313
GO:0140677
GO:0140678
GO:1902806
GO:1904706
GO:1905179
GO:2000045
GO:2000134
GO:2000278
GO:2000279
GO:2000379
ILMN_1214871
ILMN_2634083
ILMN_2846775
ILMN_2846776
Msa.1362.0_f_at
mMC021344
mMR028209
u09507_f_at
w82380_s_at
Participates
as an input of
CEBPA binds CDKN1A (p21) (Mus musculus)
as a component of
CEBPA:CDKN1A [nucleoplasm] (Mus musculus)
as an output of
Translocation of p21 to the nucleus (Mus musculus)
as a member of
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Mus musculus)
CDKN1A,CDKN1B [nucleoplasm] (Mus musculus)
Other forms of this molecule
phospho-Cdkn1a [cytosol]
phospho-Cdkn1a [cytosol]
Cdkn1a [cytosol]
phospho-Cdkn1a [nucleoplasm]
Inferred From
CDKN1A [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_031695.1
,
NP_001104569.1
Ensembl
ENSMUST00000119901
,
ENSMUSP00000113150
,
ENSMUST00000023829
,
ENSMUSP00000156559
,
ENSMUST00000233296
,
ENSMUSP00000023829
,
ENSMUSP00000112411
,
ENSMUST00000122348
,
ENSMUSG00000023067
PRO
P39689
MGI
104556
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17918
5
Pcna [nucleoplasm]
(R-MMU-4615861)
Pcna [nucleoplasm]
(R-MMU-8943000)
Pcna [nucleoplasm]
(R-MMU-5653768)
Pcna [nucleoplasm]
(R-MMU-5651986)
Pcna [nucleoplasm]
(R-MMU-68439)
0.524
2
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