Reactome | EPS15 [cytosol]

EPS15 [cytosol]

Stable Identifier

R-MMU-182920

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

P42567

Locations in the PathwayBrowser for interactor UniProt:Q8NFH8 REPS2

Expand all

Cell-Cell communication (Mus musculus)

- Cell junction organization (Mus musculus)
  - Cell-cell junction organization (Mus musculus)
    - Adherens junctions interactions (Mus musculus)
      - Regulation of Homotypic Cell-Cell Adhesion (Mus musculus)
        
        Regulation of Expression and Function of Type I Classical Cadherins (Mus musculus)
        
        Regulation of CDH1 Expression and Function (Mus musculus)
        
        Regulation of CDH1 Function (Mus musculus)
        
        Degradation of CDH1 (Mus musculus)
        
        The complex of MDM2 and CDH1 translocates to early endosomes (Mus musculus)
        
        EPS15 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:P42567

Reference Genes

BioGPS Gene:13858

ENSEMBL:ENSMUSG00000028552

KEGG:mmu:13858

Monarch:13858

NCBI Gene:13858

UCSC:P42567

Reference Transcript

Other Identifiers

104006_at

104367_at

10506939

110527_at

13858

1419251_at

1419252_at

1440729_at

17416830

4364647

4556346

4575799

4614341

4637585

4644876

4660341

4743563

4743854

4778583

4821465

4834425

4849043

4879976

4933800

4986478

5002031

5030396

5030887

5045655

5048515

5064017

5142265

5146157

5167942

5204124

5204428

5238653

5287814

5310376

5315609

5347282

5358827

5384191

5404760

5496743

5503373

5507050

5568284

5612501

A_51_P156243

A_52_P360595

A_55_P2483133

A_55_P2603993

A_55_P2603998

A_55_P2714916

A_55_P2815434

GE34348

GO:0001921

GO:0005509

GO:0005515

GO:0005737

GO:0005768

GO:0005769

GO:0005829

GO:0005886

GO:0005905

GO:0006895

GO:0006897

GO:0009925

GO:0015031

GO:0016020

GO:0016192

GO:0016197

GO:0016235

GO:0016324

GO:0017124

GO:0019065

GO:0030122

GO:0030132

GO:0030136

GO:0030674

GO:0031410

GO:0031593

GO:0031901

GO:0032456

GO:0032880

GO:0042127

GO:0042802

GO:0043130

GO:0045202

GO:0046718

GO:0046872

GO:0048268

GO:0060090

GO:0060170

GO:0065003

GO:0070086

GO:0098843

GO:0098884

GO:0098978

ILMN_1228338

ILMN_1258559

L21768_s_at

mMC016350

mMR026252

Participates

as a component of

as a member of

EPS15,EPN1,EPN2 [cytosol] (Mus musculus)

This entity regulates

Positively

The complex of MDM2 and CDH1 translocates to early endosomes (Mus musculus)

Other forms of this molecule

phospho-p-Y849 EPS15 [cytosol]

Inferred From

EPS15 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_031969.1, NP_001153436.1

ENSEMBL

ENSMUSP00000099790, ENSMUST00000102729, ENSMUSG00000028552

PRO

P42567

GlyGen

P42567

MGI

104583

PDB

1QJT, 1KYF, 1KYU

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P17427	7	AP2A2(1-939) [endolysosome membrane] (R-MMU-6784819) AP2A2(1-939) [ficolin-1-rich granule membrane] (R-MMU-6800414) AP2A2(1-939) [secretory granule membrane] (R-MMU-6800412) AP2A2-3 [endocytic vesicle membrane] (R-MMU-416635) AP2A2(1-939) [plasma membrane] (R-MMU-177502) AP2A2(1-939) [clathrin-coated endocytic vesicle membrane] (R-MMU-5138448) AP2A2(1-939) [cytosol] (R-MMU-182155)	0.676	3
UniProt:Q8NFH8 REPS2	1	REPS2 [cytosol] (R-HSA-432938)	0.544	10

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