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Foxo1 [nucleoplasm]
Stable Identifier
R-MMU-187293
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
External Reference Information
External Reference
UniProt:Q9R1E0 Foxo1
Gene Names
Foxo1, Fkhr, Foxo1a
Chain
chain:1-652
Reference Genes
BioGPS Gene:56458 Foxo1
KEGG:mmu:56458 Foxo1
Monarch:56458 Foxo1
NCBI Gene:56458 Foxo1
UCSC:Q9R1E0 Foxo1
Reference Transcript
RefSeq:NM_019739.3 Foxo1
Other Identifiers
10491962
1416981_at
1416982_at
1416983_s_at
162780_at
17397497
4426656
4539449
4966966
4983822
4987758
5081625
5220900
5331475
5491261
5557056
56458
A_51_P138044
A_52_P453884
GE37497
GO:0000122
GO:0000978
GO:0000981
GO:0001223
GO:0001227
GO:0001228
GO:0001568
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006111
GO:0006355
GO:0006357
GO:0006914
GO:0006915
GO:0006974
GO:0008013
GO:0008134
GO:0008286
GO:0009267
GO:0010467
GO:0010508
GO:0012501
GO:0030154
GO:0031490
GO:0031625
GO:0032868
GO:0032869
GO:0032873
GO:0034393
GO:0034599
GO:0042127
GO:0042593
GO:0043065
GO:0043066
GO:0043226
GO:0043565
GO:0045599
GO:0045722
GO:0045732
GO:0045893
GO:0045944
GO:0046676
GO:0048856
GO:0051721
GO:0060070
GO:0060260
GO:0070166
GO:0070301
GO:0070542
GO:0071455
GO:0071549
GO:0071732
GO:0090090
GO:0097150
GO:0140110
GO:1902617
GO:1903243
GO:1990841
GO:2000177
GO:2000377
ILMN_2509340
ILMN_2656498
mMC014112
mMR029123
Participates
as an input of
CREBBP acetylates Foxo1 (Homo sapiens)
Foxo1 binds Agrp gene promoter (Mus musculus)
Foxo1 and Sin3a:Hdac complex bind Gck gene promoter (Mus musculus)
Foxo1 binds Retn gene (Mus musculus)
Foxo1 and Nr3c1 bind Trim63 gene promoter (Mus musculus)
Foxo1 binds Ppargc1a (Mus musculus)
Foxo1 binds Pomc gene promoter (Mus musculus)
as an output of
Sirt1 deacetylates Foxo1 (Mus musculus)
as a component of
Foxo1:Agrp gene [nucleoplasm] (Mus musculus)
Foxo1:Sin3a:Hdac1,Hdac2 dimers [nucleoplasm] (Mus musculus)
Foxo1:Retn gene [nucleoplasm] (Mus musculus)
Foxo1:Nr3c1:(ALDO1,11DCORST,CORST,CORT) dimer:Trim63 gene [nucleoplasm] (Mus musculus)
Foxo1:Ppargc1a [nucleoplasm] (Mus musculus)
Foxo1:Pomc gene [nucleoplasm] (Mus musculus)
as a member of
Foxo1,Foxo3 [nucleoplasm] (Mus musculus)
This entity regulates
Negatively
FOXa2/HNF3b-, MafA-, and PAX6-dependent synthesis of Pdx1 protein
(Mus musculus)
FOXa2/HNF3b-, MafA-, and PAX6-dependent synthesis of Pdx1 protein
(Mus musculus)
FOXa2/HNF3b-, MafA-, and PAX6-dependent synthesis of Pdx1 protein
(Mus musculus)
Positively
Pink1 gene expression is stimulated by Foxo1
(Mus musculus)
Other forms of this molecule
phospho-Foxo1 [nucleoplasm]
Ac-K242,K245,K262-Foxo1 [nucleoplasm]
phospho-Foxo1 [cytosol]
phospho-Foxo1 [nucleoplasm]
Foxo1 [nucleoplasm]
Cross References
RefSeq
NP_062713.2
ENSEMBL
ENSMUST00000053764
,
ENSMUSP00000055308
PRO
Q9R1E0
GlyGen
Q9R1E0
MGI
1890077
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DJI6 FCOR
0.668
12
UniProt:P10275 AR
4
AR [cytosol]
(R-HSA-5618082)
AR [nucleoplasm]
(R-HSA-446174)
monoSUMO1-K386,520-AR [nucleoplasm]
(R-HSA-4090320)
PolyUb-AR [nucleoplasm]
(R-HSA-6782984)
0.592
4
UniProt:P53566 Cebpa
2
Cebpa [nucleoplasm]
(R-MMU-381289)
Cebpa [nucleoplasm]
(R-MMU-442502)
0.591
5
UniProt:Il7r ENSMUSG00000003882
0.527
2
UniProt:Q6PB66 LPPRC
0.524
2
UniProt:P31750 Akt1
12
phospho-p-T308,S473-AKT1 [nucleoplasm]
(R-MMU-198357)
phospho-p-T308,S473-AKT1 [cytosol]
(R-MMU-198356)
phospho-p-S473-AKT1 [plasma membrane]
(R-MMU-377265)
AKT1 [plasma membrane]
(R-MMU-199416)
AKT1 [cytosol]
(R-MMU-58252)
phospho-p-T308-AKT1 [cytosol]
(R-MMU-198634)
phospho-p-Y315,Y326-AKT1 [cytosol]
(R-MMU-8848757)
phospho-p-T308,S473-AKT1 [plasma membrane]
(R-MMU-199430)
p-T308,S473-Akt1 [cytosol]
(R-MMU-162346)
Akt1 [cytosol]
(R-MMU-189709)
phospho-p-S473-AKT1 [cytosol]
(R-MMU-9841264)
p-T308,S473-Akt1 [plasma membrane]
(R-MMU-1445123)
0.462
4
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