Reactome | Racgap1 [cytosol]

Racgap1 [cytosol]

Stable Identifier

R-MMU-195122

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

RACGAP1, Q9WVM1

Locations in the PathwayBrowser

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Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Mus musculus)
    - Golgi-to-ER retrograde transport (Mus musculus)
      - COPI-dependent Golgi-to-ER retrograde traffic (Mus musculus)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Mus musculus)
        
        Kinesins:microtubule [cytosol] (Mus musculus)
        
        Kinesins [cytosol] (Mus musculus)
        
        Centralspindlin [cytosol] (Mus musculus)
        
        Racgap1 [cytosol] (Mus musculus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Mus musculus)
        
        Kinesins:microtubule [cytosol] (Mus musculus)
        
        Kinesins [cytosol] (Mus musculus)
        
        Centralspindlin [cytosol] (Mus musculus)
        
        Racgap1 [cytosol] (Mus musculus)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Mus musculus)
        
        Kinesins:microtubule [cytosol] (Mus musculus)
        
        Kinesins [cytosol] (Mus musculus)
        
        Centralspindlin [cytosol] (Mus musculus)
        
        Racgap1 [cytosol] (Mus musculus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Mus musculus)
        
        Kinesins:microtubule [cytosol] (Mus musculus)
        
        Kinesins [cytosol] (Mus musculus)
        
        Centralspindlin [cytosol] (Mus musculus)
        
        Racgap1 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9WVM1

Gene Names

Racgap1

Reference Genes

BioGPS Gene:26934 Racgap1

ENSEMBL:ENSMUSG00000023015

KEGG:mmu:26934 Racgap1

Monarch:26934 Racgap1

NCBI Gene:26934 Racgap1

UCSC:Q9WVM1 Racgap1

Reference Transcript

Other Identifiers

10432511

1421546_a_at

1451358_a_at

17321597

26934

4307683

4337642

4448165

4457835

4513235

4560097

4604631

4607484

4613312

4657432

4719899

4816267

4881092

4916829

5148399

5161020

5195818

5322960

5342204

5352855

5393480

5427856

5427962

5447374

5510065

5544760

5583055

94953_at

A_51_P243750

A_52_P298465

A_55_P2127702

A_55_P2596289

GE35980

GO:0000281

GO:0000910

GO:0000915

GO:0001669

GO:0005096

GO:0005547

GO:0005634

GO:0005654

GO:0005737

GO:0005819

GO:0005856

GO:0005886

GO:0006811

GO:0007010

GO:0007165

GO:0007266

GO:0007283

GO:0007405

GO:0008017

GO:0008092

GO:0008272

GO:0008289

GO:0009898

GO:0019901

GO:0022414

GO:0030154

GO:0030218

GO:0030496

GO:0030674

GO:0031410

GO:0032154

GO:0032467

GO:0043014

GO:0043015

GO:0043226

GO:0045995

GO:0046872

GO:0048487

GO:0051233

GO:0051256

GO:0051301

GO:0051988

GO:0060090

GO:0072686

GO:0090543

GO:0097149

GO:0098772

ILMN_1243705

ILMN_2634078

Msa.37104.0_s_at

aa049623_s_at

mMC002663

Participates

as a candidate of

as a member of

as an input of

Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Mus musculus)

as a component of

Centralspindlin [cytosol] (Mus musculus)

Inferred From

RACGAP1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSMUSG00000023015, ENSMUST00000171702, ENSMUSP00000126417, ENSMUST00000023756, ENSMUSP00000023756

PRO

Q9WVM1

MGI

1349423

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q02241 KIF23	3	KIF23 [nucleoplasm] (R-HSA-156709) p-S911,S912-KIF23 [nucleoplasm] (R-HSA-156695) KIF23 [cytosol] (R-HSA-1015863)	0.564	2
UniProt:Q8NEM2 SHCBP			0.564	2
UniProt:P16054	2	PRKCE [cytosol] (R-MMU-58202) phospho-p-T566,T710,S729-PRKCE [plasma membrane] (R-MMU-198260)	0.524	2