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Phosphorylated ERBB2:EGFR heterodimers [plasma membrane]
Stable Identifier
R-MMU-1963587
Type
Set [CandidateSet]
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
Negative regulation of the PI3K/AKT network (Mus musculus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
Activator:PI3K [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
Activator:PI3K [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
RAS GEFs promote RAS nucleotide exchange (Mus musculus)
RAS GEFs [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by ERBB2 (Mus musculus)
Downregulation of ERBB2 signaling (Mus musculus)
PTPN18 binds ERBB2:EGFR heterodimers (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
PI3K events in ERBB2 signaling (Mus musculus)
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Mus musculus)
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] (Mus musculus)
Participants
members
EGF:p-6Y-EGFR:p-6Y,Y1112-ERBB2 [plasma membrane]
(Mus musculus)
candidates
EGF:p-6Y-EGFR:p-7Y,Y1112-ERBB2 [plasma membrane]
(Mus musculus)
Participates
as an input of
PTPN18 binds ERBB2:EGFR heterodimers (Mus musculus)
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Mus musculus)
as a component of
Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Mus musculus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Mus musculus)
Inferred From
Phosphorylated ERBB2:EGFR heterodimers [plasma membrane]
(Homo sapiens)
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