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PARP1 [nucleoplasm]
Stable Identifier
R-MMU-201568
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
P11103
Locations in the PathwayBrowser for interactor UniProt:Q9WTL8 Arntl
Expand all
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
PARP1 ADP-ribosylates SMAD3 and SMAD4 (Mus musculus)
PARP1 [nucleoplasm] (Mus musculus)
PARP1 binds SMAD2/3:SMAD4 heterotrimer (Mus musculus)
PARP1 [nucleoplasm] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
SUMOylation (Mus musculus)
SUMO E3 ligases SUMOylate target proteins (Mus musculus)
SUMOylation of DNA damage response and repair proteins (Mus musculus)
PIAS4 SUMOylates PARP1 with SUMO1 (Mus musculus)
PARP1 [nucleoplasm] (Mus musculus)
PIAS4 SUMOylates PARP1 with SUMO2,3 (Mus musculus)
PARP1 [nucleoplasm] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by TGFB family members (Mus musculus)
Signaling by TGF-beta Receptor Complex (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
PARP1 ADP-ribosylates SMAD3 and SMAD4 (Mus musculus)
PARP1 [nucleoplasm] (Mus musculus)
PARP1 binds SMAD2/3:SMAD4 heterotrimer (Mus musculus)
PARP1 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P11103
Reference Genes
ENSEMBL:ENSMUSG00000026496
UCSC:P11103
Participates
as an input of
PIAS4 SUMOylates PARP1 with SUMO2,3 (Mus musculus)
PIAS4 SUMOylates PARP1 with SUMO1 (Mus musculus)
PARP1 binds SMAD2/3:SMAD4 heterotrimer (Mus musculus)
as a member of
PARP1,PARP2 [nucleoplasm] (Mus musculus)
as an output of
PARP1 ADP-ribosylates SMAD3 and SMAD4 (Mus musculus)
as a component of
p-2S-SMAD2,3:SMAD4:PARP1 [nucleoplasm] (Mus musculus)
Other forms of this molecule
polySUMO2,3-K203,K486-PARP1 [nucleoplasm]
monoSUMO1-K203,K486-PARP1 [nucleoplasm]
PAR-PARP1 [nucleoplasm]
Inferred From
PARP1 [nucleoplasm]
(Homo sapiens)
Cross References
ZINC - Substances
PARP1_MOUSE
ZINC target
P11103
PRO
P11103
GlyGen
P11103
MGI
1340806
ZINC - Predictions - Purchasable
PARP1_MOUSE
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
IntAct:EBI-11426955 1082A
0.524
3
UniProt:P03087 VP1
0.524
2
UniProt:P70288 Hdac2
2
monoSUMO1-K462-HDAC2 [nucleoplasm]
(R-MMU-4615958)
Hdac2 [nucleoplasm]
(R-MMU-573366)
0.499
3
UniProt:P20263 Pou5f1
2
Pou5f1 [nucleoplasm]
(R-MMU-3245981)
POU5F1 [nucleoplasm]
(R-MMU-452472)
0.499
2
UniProt:Q3TKT4 Smarca4
2
Smarca4 [nucleoplasm]
(R-MMU-9727480)
SMARCA4 [nucleoplasm]
(R-MMU-201686)
0.499
2
UniProt:Q9WTL8 Arntl
4
Arntl [nucleoplasm]
(R-MMU-9769624)
Bmal1 [nucleoplasm]
(R-MMU-9634872)
Arntl [cytosol]
(R-MMU-508660)
p-S-Arntl [nucleoplasm]
(R-MMU-508690)
0.499
7
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