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Pdpk1 [cytosol]
Stable Identifier
R-MMU-202210
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
PDPK1, Q9Z2A0
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to mechanical stimuli (Mus musculus)
Response of endothelial cells to shear stress (Mus musculus)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Mus musculus)
Phosphorylation of PDPK1 on serine-241 (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
Hemostasis (Mus musculus)
Platelet activation, signaling and aggregation (Mus musculus)
GPVI-mediated activation cascade (Mus musculus)
PIP3 recruits PDPK1 to the membrane (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Regulation of T cell activation by CD28 family (Mus musculus)
Co-stimulation by CD28 (Mus musculus)
CD28 dependent PI3K/Akt signaling (Mus musculus)
PIP3 recruits PDPK1 to the membrane (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
TCR signaling (Mus musculus)
Downstream TCR signaling (Mus musculus)
Translocation of PDK1 to Plasma membrane (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
Role of LAT2/NTAL/LAB on calcium mobilization (Mus musculus)
Translocation of PDK1 to Plasma membrane (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PDPK1 binds PIP2 (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
PIP3 recruits PDPK1 to the membrane (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G-protein beta:gamma signalling (Mus musculus)
G beta:gamma signalling through PI3Kgamma (Mus musculus)
PIP3 recruits PDK1 and AKT to the membrane (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
VEGFR2 mediated vascular permeability (Mus musculus)
PIP3 recruits PDPK1 to the membrane (Mus musculus)
Pdpk1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9Z2A0
Gene Names
Pdpk1
Reference Genes
BioGPS Gene:18607 Pdpk1
ENSEMBL:ENSMUSG00000024122
KEGG:mmu:18607 Pdpk1
Monarch:18607 Pdpk1
NCBI Gene:18607 Pdpk1
UCSC:Q9Z2A0 Pdpk1
Reference Transcript
RefSeq:NM_011062.4 Pdpk1
Other Identifiers
102063_at
10342214
10448424
1415729_at
1416501_at
160578_at
17207129
17207139
17207141
17207187
17207189
17207191
17207193
17207195
17207197
17207199
17207209
17207231
17207237
17341690
18607
4354694
4409293
4417127
4420948
4506503
4566792
4571676
4619079
4619304
4768300
4800121
4823965
4845022
4862984
4865680
4894842
4898603
4901365
4939301
4969023
4981628
5003897
5173659
5228395
5281553
5303163
5320900
5339059
5408004
5462355
5484544
5534898
A_52_P111390
A_52_P111397
A_52_P619138
A_55_P2014357
A_55_P2014361
A_55_P2451183
GE35875
GO:0000166
GO:0003323
GO:0003824
GO:0004672
GO:0004674
GO:0004676
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005925
GO:0006468
GO:0006972
GO:0007165
GO:0007173
GO:0008286
GO:0010594
GO:0010667
GO:0014069
GO:0016004
GO:0016020
GO:0016301
GO:0016477
GO:0016740
GO:0019722
GO:0030512
GO:0031410
GO:0032869
GO:0034122
GO:0035556
GO:0042995
GO:0043066
GO:0043122
GO:0043226
GO:0043274
GO:0043304
GO:0043491
GO:0043536
GO:0045766
GO:0048009
GO:0048856
GO:0048870
GO:0051281
GO:0051897
GO:0070161
GO:0071364
GO:0097191
GO:0098772
GO:0106310
GO:0140096
GO:0141124
GO:1903078
GO:1903672
GO:1905564
GO:2000352
ILMN_2594855
ILMN_2594857
ILMN_3124885
Msa.34345.0_s_at
mMC001938
Participates
as an input of
Phosphorylation of PDPK1 on serine-241 (Mus musculus)
PIP3 recruits PDK1 and AKT to the membrane (Mus musculus)
PDPK1 binds PIP2 (Mus musculus)
Translocation of PDK1 to Plasma membrane (Mus musculus)
PIP3 recruits PDPK1 to the membrane (Mus musculus)
Other forms of this molecule
phospho-Pdpk1 [cytosol]
Pdpk1 [plasma membrane]
Inferred From
PDPK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_035192.2
ENSEMBL
ENSMUSP00000099991
,
ENSMUST00000102927
,
ENSMUSG00000024122
IntEnz
2.7.11.1
PRO
Q9Z2A0
GlyGen
Q9Z2A0
MGI
1338068
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