Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ITK [cytosol]
Stable Identifier
R-MMU-202319
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q03526
Locations in the PathwayBrowser for interactor UniProt:Q13094 LCP2
Expand all
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
TCR signaling (Mus musculus)
Generation of second messenger molecules (Mus musculus)
Recruitment of ITK to SLP-76 (Mus musculus)
ITK [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q03526 Itk
Gene Names
Itk, Emt, Tlk, Tsk
Chain
chain:1-625
Reference Genes
BioGPS Gene:16428 Itk
ENSEMBL:ENSMUSG00000020395.14 Itk
KEGG Gene (Mus musculus):16428 Itk
Monarch:16428 Itk
NCBI Gene:16428 Itk
UCSC:Q03526 Itk
Reference Transcript
RefSeq:NM_010583.3 Itk
RefSeq:NM_001281966.1 Itk
RefSeq:NM_001281968.1 Itk
RefSeq:NM_001281965.1 Itk
Other Identifiers
103028_at
10385428
1417171_at
1452518_a_at
16428
17262102
4324615
4366432
4474256
4481190
4523796
4530289
4637610
4637630
4645579
4717920
4775294
4879399
4885822
4933443
5202369
5203612
5216003
5260606
5460168
5537634
5541459
5575375
A_51_P342688
A_52_P50623
A_55_P1953788
A_55_P2178818
GO:0000166
GO:0001819
GO:0001865
GO:0002250
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005911
GO:0006468
GO:0007202
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030154
GO:0035556
GO:0036211
GO:0043226
GO:0046629
GO:0046872
GO:0048856
GO:0050852
GO:0050853
GO:0140096
ILMN_1252472
ILMN_2613422
d14042_s_at
mMC008330
mMR027115
Participates
as a member of
TEC,BTK,ITK,(TXK) [cytosol] (Mus musculus)
as an input of
Recruitment of ITK to SLP-76 (Mus musculus)
as a component of
ITK:p-Y113,128,145-SLP-76:GADS:LAT [plasma membrane] (Mus musculus)
Other forms of this molecule
Itk [cytosol]
phospho-p-Y180,Y512-ITK [cytosol]
phospho-p-Y512-ITK [cytosol]
Inferred From
ITK [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_034713.2
,
NP_001268895.1
,
NP_001268894.1
,
NP_001268897.1
Ensembl
ENSMUSG00000020395
,
ENSMUST00000109237
,
ENSMUSP00000104860
PRO
Q03526
MGI
96621
PDB
2K7A
,
2EU0
,
1LUI
,
2RN8
,
1AWJ
,
2RNA
,
1LUK
,
1LUN
,
2K79
,
2ETZ
,
1LUM
,
3S9K
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08487 PLCG1
0.618
4
UniProt:Q13094 LCP2
2
p-Y113,128,145-LCP2 [cytosol]
(R-HSA-202175)
LCP2 [cytosol]
(R-HSA-202306)
0.524
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text