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SMAD3 [nucleoplasm]
Stable Identifier
R-MMU-206150
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
Q8BUN5
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
Dephosphorylated SMAD2/3 translocates to the cytosol (Mus musculus)
SMAD2,3 [nucleoplasm] (Mus musculus)
SMAD3 [nucleoplasm] (Mus musculus)
PPM1A dephosphorylates nuclear SMAD2/3 (Mus musculus)
SMAD2,3 [nucleoplasm] (Mus musculus)
SMAD3 [nucleoplasm] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by TGFB family members (Mus musculus)
Signaling by TGF-beta Receptor Complex (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
Dephosphorylated SMAD2/3 translocates to the cytosol (Mus musculus)
SMAD2,3 [nucleoplasm] (Mus musculus)
SMAD3 [nucleoplasm] (Mus musculus)
PPM1A dephosphorylates nuclear SMAD2/3 (Mus musculus)
SMAD2,3 [nucleoplasm] (Mus musculus)
SMAD3 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8BUN5 Smad3
Gene Names
Smad3, Madh3
Chain
initiator methionine:, chain:2-425
Reference Genes
BioGPS Gene:17127 Smad3
ENSEMBL:ENSMUSG00000032402.13 Smad3
KEGG Gene (Mus musculus):17127 Smad3
Monarch:17127 Smad3
NCBI Gene:17127 Smad3
UCSC:Q8BUN5 Smad3
Reference Transcript
RefSeq:NM_016769.4 Smad3
Other Identifiers
10594404
112401_at
1450471_at
1450472_s_at
1454960_at
17127
17528111
4426861
4550346
4552626
4594059
4669844
4680701
4744028
4895408
4902713
5059743
5100353
5103926
5173715
5192794
5303592
5305645
5377259
5504918
5552183
5602305
93613_at
AF016189_at
A_51_P441022
A_52_P352277
A_55_P2101001
GE37043
GO:0000122
GO:0000165
GO:0000785
GO:0000976
GO:0000977
GO:0000978
GO:0000981
GO:0000987
GO:0001217
GO:0001222
GO:0001223
GO:0001228
GO:0001501
GO:0001649
GO:0001657
GO:0001666
GO:0001701
GO:0001707
GO:0001756
GO:0001889
GO:0001947
GO:0002076
GO:0002376
GO:0002520
GO:0003012
GO:0003013
GO:0003677
GO:0003682
GO:0003690
GO:0003700
GO:0005160
GO:0005515
GO:0005518
GO:0005634
GO:0005635
GO:0005637
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006357
GO:0006954
GO:0006955
GO:0007010
GO:0007155
GO:0007179
GO:0007254
GO:0007369
GO:0007492
GO:0008013
GO:0008270
GO:0008285
GO:0009653
GO:0009880
GO:0010628
GO:0010629
GO:0010718
GO:0012501
GO:0016202
GO:0016922
GO:0017015
GO:0017151
GO:0019899
GO:0019901
GO:0019902
GO:0023019
GO:0023052
GO:0030154
GO:0030163
GO:0030198
GO:0030308
GO:0030325
GO:0030335
GO:0030501
GO:0030878
GO:0031490
GO:0031625
GO:0031962
GO:0032332
GO:0032731
GO:0032810
GO:0032909
GO:0032916
GO:0032924
GO:0033689
GO:0034330
GO:0035259
GO:0038092
GO:0042060
GO:0042110
GO:0042177
GO:0042802
GO:0042803
GO:0043066
GO:0043130
GO:0043226
GO:0043235
GO:0043425
GO:0043565
GO:0045216
GO:0045429
GO:0045599
GO:0045668
GO:0045893
GO:0045944
GO:0046872
GO:0048340
GO:0048589
GO:0048617
GO:0048701
GO:0048856
GO:0048870
GO:0050678
GO:0050728
GO:0050776
GO:0050821
GO:0050927
GO:0051481
GO:0051496
GO:0051894
GO:0060039
GO:0060290
GO:0060395
GO:0061045
GO:0061629
GO:0061767
GO:0070306
GO:0070410
GO:0070411
GO:0070412
GO:0071141
GO:0071144
GO:0071333
GO:0071560
GO:0090263
GO:0097191
GO:0098586
GO:0140110
GO:0140297
GO:1901203
GO:1902894
GO:1902895
GO:1903243
GO:1990776
GO:1990841
ILMN_2772582
ILMN_2938893
mMC010715
Participates
as a member of
SMAD2,3 [nucleoplasm] (Mus musculus)
Other forms of this molecule
Ub-SMAD3 [cytosol]
Smad3 [nucleoplasm]
phospho-p-S208-SMAD3 [cytosol]
phospho-2xADPRib-p-S423,S425-SMAD3 [nucleoplasm]
phospho-Ub,p-T179,S423,S425-SMAD3 [nucleoplasm]
phospho-p-T179,S423,S425-SMAD3 [nucleoplasm]
SMAD3 [cytosol]
p-S423,425-Smad3 [cytosol]
p-S423,425-Smad3 [nucleoplasm]
Inferred From
SMAD3 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_058049.3
Ensembl
ENSMUSG00000032402
,
ENSMUST00000034973
,
ENSMUSP00000034973
PRO
Q8BUN5
MGI
1201674
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Foxp3 ENSMUSG00000039521
0.837
7
UniProt:P97471 Smad4
6
Smad4 [nucleoplasm]
(R-MMU-1225891)
phospho-RibC-SMAD4 [nucleoplasm]
(R-MMU-2187323)
Ub-SMAD4 [nucleoplasm]
(R-MMU-9773863)
Ub-SMAD4 [cytosol]
(R-MMU-9773859)
SMAD4 [cytosol]
(R-MMU-170862)
SMAD4 [nucleoplasm]
(R-MMU-177103)
0.731
6
UniProt:P20263 Pou5f1
2
Pou5f1 [nucleoplasm]
(R-MMU-3245981)
POU5F1 [nucleoplasm]
(R-MMU-452472)
0.597
13
UniProt:Q9Y2U8 LEMD3
4
LEMD3 [endosome membrane]
(R-HSA-9715091)
LEMD3 [endoplasmic reticulum membrane]
(R-HSA-9714458)
LEMD3 [plasma membrane]
(R-HSA-9715186)
LEMD3 [nuclear envelope]
(R-HSA-2993886)
0.564
2
IntAct:EBI-2479619 SMAD7
0.527
3
IntAct:EBI-5259554 IL2RA
0.527
2
UniProt:P10085 Myod1
2
MYOD1_MOUSE [nucleoplasm]
(R-MMU-448840)
Myod1 [nucleoplasm]
(R-MMU-445441)
0.462
6
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