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Gpc3 [Golgi lumen]
Stable Identifier
R-MMU-2064012
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
Golgi lumen
Synonyms
GlcA-Gal-Gal-Xyl-GPC3, Q8CFZ4
Locations in the PathwayBrowser
Expand all
Metabolism (Mus musculus)
Metabolism of carbohydrates (Mus musculus)
Glycosaminoglycan metabolism (Mus musculus)
Chondroitin sulfate/dermatan sulfate metabolism (Mus musculus)
A tetrasaccharide linker sequence is required for GAG synthesis (Mus musculus)
B3GAT dimers transfer GlcA to tetrasaccharide linker (Mus musculus)
GlcA-Gal-Gal-Xyl-proteins [Golgi lumen] (Mus musculus)
Gpc3 [Golgi lumen] (Mus musculus)
B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Mus musculus)
GlcA-Gal-Gal-Xyl-proteins [Golgi lumen] (Mus musculus)
Gpc3 [Golgi lumen] (Mus musculus)
Heparan sulfate/heparin (HS-GAG) metabolism (Mus musculus)
A tetrasaccharide linker sequence is required for GAG synthesis (Mus musculus)
B3GAT dimers transfer GlcA to tetrasaccharide linker (Mus musculus)
GlcA-Gal-Gal-Xyl-proteins [Golgi lumen] (Mus musculus)
Gpc3 [Golgi lumen] (Mus musculus)
B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Mus musculus)
GlcA-Gal-Gal-Xyl-proteins [Golgi lumen] (Mus musculus)
Gpc3 [Golgi lumen] (Mus musculus)
HS-GAG biosynthesis (Mus musculus)
EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue (Mus musculus)
GlcA-Gal-Gal-Xyl-HS proteins [Golgi lumen] (Mus musculus)
Gpc3 [Golgi lumen] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8CFZ4 Gpc3
Gene Names
Gpc3
Chain
signal peptide:1-24, chain:25-357, chain:358-553, propeptide:554-579
Reference Genes
BioGPS Gene:14734 Gpc3
ENSEMBL:ENSMUSG00000055653.14 Gpc3
KEGG Gene (Mus musculus):14734 Gpc3
Monarch:14734 Gpc3
NCBI Gene:14734 Gpc3
UCSC:Q8CFZ4 Gpc3
Reference Transcript
RefSeq:NM_016697.3 Gpc3
Other Identifiers
10604576
1450990_at
14734
160158_at
17541681
4391132
4543654
4565815
4634951
4674976
4681583
4739201
4819559
4895569
4948114
5111632
5263860
A_52_P23225
GE36974
GO:0001658
GO:0001822
GO:0005515
GO:0005764
GO:0005773
GO:0005794
GO:0005796
GO:0005886
GO:0007224
GO:0008285
GO:0009617
GO:0009887
GO:0009948
GO:0009966
GO:0009986
GO:0010171
GO:0016020
GO:0016192
GO:0016477
GO:0023052
GO:0030154
GO:0030163
GO:0030282
GO:0030312
GO:0030316
GO:0030324
GO:0030414
GO:0030513
GO:0031012
GO:0035116
GO:0040008
GO:0042074
GO:0043226
GO:0045732
GO:0045807
GO:0045879
GO:0045880
GO:0045926
GO:0046326
GO:0048856
GO:0048870
GO:0050673
GO:0050680
GO:0055085
GO:0060070
GO:0060071
GO:0060422
GO:0060828
GO:0060976
GO:0062023
GO:0072111
GO:0072138
GO:0072180
GO:0072203
GO:0090090
GO:0090263
GO:0098552
GO:0098772
GO:1905475
GO:2000050
GO:2000096
ILMN_2719973
ILMN_2832979
mMC011305
Participates
as a member of
GlcA-Gal-Gal-Xyl-HS proteins [Golgi lumen] (Mus musculus)
GlcA-Gal-Gal-Xyl-proteins [Golgi lumen] (Mus musculus)
Other forms of this molecule
Gpc3 [lysosomal lumen]
Gpc3 [lysosomal lumen]
HS(1)-Gpc3 [Golgi lumen]
HS(2)-Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [plasma membrane]
Gpc3 [plasma membrane]
Gpc3 [plasma membrane]
Gpc3 [plasma membrane]
Gpc3 [plasma membrane]
Gpc3 [plasma membrane]
Gpc3 [endoplasmic reticulum lumen]
phospho-Gpc3 [endoplasmic reticulum lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Gpc3 [Golgi lumen]
Inferred From
GlcA-Gal-Gal-Xyl-GPC3 [Golgi lumen]
(Homo sapiens)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63505) at unknown position
Modification
beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
NP_057906.2
Ensembl
ENSMUSG00000055653
,
ENSMUST00000069360
,
ENSMUSP00000064131
PRO
Q8CFZ4
MGI
104903
PDB
7ZA3
,
7ZAV
,
7ZA2
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