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PTPN1 [cytosol]
Stable Identifier
R-MMU-210625
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
P35821
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to mechanical stimuli (Mus musculus)
Response of endothelial cells to shear stress (Mus musculus)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Mus musculus)
PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
Hemostasis (Mus musculus)
Platelet activation, signaling and aggregation (Mus musculus)
Platelet Aggregation (Plug Formation) (Mus musculus)
Integrin signaling (Mus musculus)
Dephosphorylation of inactive SRC by PTPB1 (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Growth hormone receptor signaling (Mus musculus)
PTP1B binds the GH receptor complex (Mus musculus)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
PTP1B dephosphorylates GHR (Mus musculus)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
Interferon Signaling (Mus musculus)
Interferon alpha/beta signaling (Mus musculus)
Regulation of IFNA/IFNB signaling (Mus musculus)
Dephosphorylation of TYK2 by PTP1B (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Integrin signaling (Mus musculus)
Dephosphorylation of inactive SRC by PTPB1 (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
Signaling by Non-Receptor Tyrosine Kinases (Mus musculus)
Signaling by PTK6 (Mus musculus)
PTK6 Down-Regulation (Mus musculus)
PTPN1 binds PTK6 (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
p-Y342-PTK6:PTPN1 [cytosol] (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
PTPN1 dephosphorylates PTK6 (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
p-Y342-PTK6:PTPN1 [cytosol] (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by MET (Mus musculus)
Negative regulation of MET activity (Mus musculus)
PTPN1 and PTPN2 dephosphorylate MET (Mus musculus)
PTPN1,PTPN2 [cytosol] (Mus musculus)
PTPN1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P35821 Ptpn1
Gene Names
Ptpn1
Chain
chain:1-432
Reference Genes
BioGPS Gene:19246 Ptpn1
ENSEMBL:ENSMUSG00000027540.14 Ptpn1
KEGG Gene (Mus musculus):19246 Ptpn1
Monarch:19246 Ptpn1
NCBI Gene:19246 Ptpn1
UCSC:P35821 Ptpn1
Reference Transcript
RefSeq:NM_011201.3 Ptpn1
Other Identifiers
10478897
112015_at
1417068_a_at
1438670_at
17379960
19246
4316952
4363252
4379562
4499695
4670733
4852345
4874192
4904674
4921094
4960582
5182964
5202393
5228379
5413995
5493312
5504571
5508786
5586556
94929_at
A_51_P241705
A_52_P516021
A_55_P2097111
GE35968
GO:0003824
GO:0004721
GO:0004725
GO:0004726
GO:0005158
GO:0005737
GO:0005739
GO:0005759
GO:0005768
GO:0005769
GO:0005783
GO:0005789
GO:0005829
GO:0005886
GO:0006470
GO:0006886
GO:0007010
GO:0008270
GO:0008286
GO:0009966
GO:0012501
GO:0016020
GO:0016192
GO:0016311
GO:0016787
GO:0016791
GO:0019899
GO:0019901
GO:0023052
GO:0030036
GO:0030061
GO:0030100
GO:0030948
GO:0030968
GO:0030971
GO:0031410
GO:0031904
GO:0032991
GO:0033157
GO:0034976
GO:0035335
GO:0035791
GO:0036211
GO:0036498
GO:0038020
GO:0043226
GO:0043507
GO:0046626
GO:0046875
GO:0051721
GO:0070373
GO:0097443
GO:0098554
GO:0140096
GO:1902202
GO:1902236
GO:1903898
GO:1990264
GO:2000646
ILMN_1222917
ILMN_1242726
mMC014243
mMR026755
u24700_s_at
Participates
as a component of
Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Mus musculus)
Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Mus musculus)
p-Y342-PTK6:PTPN1 [cytosol] (Mus musculus)
as an input of
PTP1B binds the GH receptor complex (Mus musculus)
PTPN1 binds PTK6 (Mus musculus)
as a member of
PTPN1,PTPN2 [cytosol] (Mus musculus)
as an output of
PTPN1 dephosphorylates PTK6 (Mus musculus)
Other forms of this molecule
Ptp1b [cytosol]
PTPN1 [endosome membrane]
Inferred From
PTPN1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_035331.3
ZINC - Substances
PTN1_MOUSE
ZINC target
P35821
Ensembl
ENSMUSG00000027540
,
ENSMUST00000029053
,
ENSMUSP00000029053
PRO
P35821
ZINC - Predictions - Purchasable
PTN1_MOUSE
MGI
97805
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