Phosphorylated STAT5A dimer is dephosphorylated by PTP1B

Stable Identifier
R-MMU-210644
Type
Reaction [transition]
Species
Mus musculus
Compartment
cytosol
ReviewStatus
5/5
General
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PNG
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 | PPTX  | SBGN
Phosphorylated STAT5A dimer is dephosphorylated by PTP1B
In mice, phosphorylated STAT5A dimer is dephosphorylated at Tyr694 by protein tyrosine phosphatase, PTP1B, in the cytosol. This results in the dissociation of the dimer in the cytosol.
Literature References
Participants
Input
Output
Catalyst Activity

protein tyrosine phosphatase activity of Ptp1b [cytosol]

Physical Entity
Ptp1b [cytosol] (Mus musculus)
Activity
protein tyrosine phosphatase activity (GO:0004725)
Orthologous Events
Phosphorylated STAT92E dimer is dephosphorylated by PTP61F isoform 1 (Drosophila melanogaster)
Authored
Williams, MG  (2006-11-02)
Reviewed
Perrimon, N  (2008-01-16)
Created
Williams, MG  (2008-01-15)
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