Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Src family tyrosine kinases (SFKs) [cytosol]
Stable Identifier
R-MMU-211064
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Hemostasis (Mus musculus)
Cell surface interactions at the vascular wall (Mus musculus)
PECAM1 interactions (Mus musculus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Regulation of T cell activation by CD28 family (Mus musculus)
Co-inhibition by CTLA4 (Mus musculus)
Phosphorylation of CTLA-4 (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
SHP2 phosphatase binds CTLA-4 (Mus musculus)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
pCTLA-4:Src kinases:SHP2 [plasma membrane] (Mus musculus)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Co-stimulation by CD28 (Mus musculus)
Phosphorylation of CD28 (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by SCF-KIT (Mus musculus)
Dimerization of STATs (Mus musculus)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Disassociation and translocation of STATs to the nucleus (Mus musculus)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
GRB2 is indirectly recruited to p-KIT through SHP2 (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Indirect recruitment of GAB2 to p-KIT (Mus musculus)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Mus musculus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
JAK2 binds to p-KIT (Mus musculus)
JAK2:SFKS:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Phosphorylation and activation of VAV1 (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Phosphorylation of GAB2 by SFKs (Mus musculus)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Phosphorylation of JAK2 (Mus musculus)
JAK2:SFKS:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Phosphorylation of SHP2 by SFKs (Mus musculus)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Phosphorylation of STATs (Mus musculus)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Phosphorylation of p-KIT on Y900 by Src kinases (Mus musculus)
SFKs:p-8Y-KIT:sSCF dimer:p-8Y-KIT [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Recruitment of STATs (Mus musculus)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Regulation of KIT signaling (Mus musculus)
Interaction of APS and p-KIT (Mus musculus)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Phosphorylation of APS (Mus musculus)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
p-APS dimer:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Recruitment of CBL to KIT (Mus musculus)
CBL:Grb2/p-APS:p-c-Kit complex [plasma membrane] (Mus musculus)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Mus musculus)
p-APS dimer:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Mus musculus)
p-APS dimer:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
SHP2 interacts with p-KIT (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Synthesis of PIP3 from PIP2 by PI3K (Mus musculus)
PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
p-SHP2:p-KIT complex [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Src family tyrosine kinases (SFKs) [cytosol] (Mus musculus)
Participants
members
Fyn [cytosol]
(Mus musculus)
Lyn [cytosol]
(Mus musculus)
YES1 [cytosol]
(Mus musculus)
SRC-2 [cytosol]
(Mus musculus)
LCK [cytosol]
(Mus musculus)
Participates
as an input of
Phosphorylation of CTLA-4 (Mus musculus)
as a component of
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Mus musculus)
SFKs:p-8Y-KIT:sSCF dimer:p-8Y-KIT [plasma membrane] (Mus musculus)
SFKs:p-KIT complex [plasma membrane] (Mus musculus)
Inferred From
Src family tyrosine kinases (SFKs) [cytosol]
(Homo sapiens)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
