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Nedd4l [nucleoplasm]
Stable Identifier
R-MMU-2176420
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
NEDD4L, Q8CFI0
Locations in the PathwayBrowser for interactor UniProt:Q99N57
Expand all
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
NEDD4L binds phosphorylated linker region of SMAD2/3 (Mus musculus)
Nedd4l [nucleoplasm] (Mus musculus)
NEDD4L ubiquitinates SMAD2/3 (Mus musculus)
Nedd4l [nucleoplasm] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by TGFB family members (Mus musculus)
Signaling by TGF-beta Receptor Complex (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
NEDD4L binds phosphorylated linker region of SMAD2/3 (Mus musculus)
Nedd4l [nucleoplasm] (Mus musculus)
NEDD4L ubiquitinates SMAD2/3 (Mus musculus)
Nedd4l [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8CFI0
Gene Names
Nedd4l
Reference Genes
ENSEMBL:ENSMUSG00000024589
UCSC:Q8CFI0 Nedd4l
Other Identifiers
103906_f_at
103907_at
10456254
1423269_a_at
1423270_at
1437400_at
1441305_at
1456044_at
1457374_at
17351282
4306640
4315269
4389616
4445244
4457647
4462914
4489470
4511807
4529850
4532147
4533246
4559234
4583070
4593273
4615578
4623661
4638892
4679137
4694334
4708819
4723466
4751684
4764370
4785146
4794705
4814688
4834969
4836449
4841142
4861554
4888945
4890591
4915393
4917809
4922703
4946591
4952755
4968149
4971835
4979649
4982425
4996880
4997551
5007352
5089479
5094470
5138430
5148609
5155656
5158254
5159564
5170497
5173731
5186988
5190049
5192355
5213008
5217256
5229502
5257865
5264865
5303023
5304868
5307142
5325963
5353744
5360636
5381922
5403672
5424045
5481654
5503658
5518417
5542869
5554166
5602940
83814
A_52_P544878
A_55_P2030752
A_55_P2030756
A_55_P2730451
A_55_P2741444
A_66_P133816
GE41705
GO:0002028
GO:0003085
GO:0003254
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005737
GO:0005768
GO:0005771
GO:0005794
GO:0005886
GO:0006511
GO:0006513
GO:0006814
GO:0009651
GO:0010765
GO:0010766
GO:0015459
GO:0016567
GO:0016740
GO:0017080
GO:0019870
GO:0019871
GO:0030154
GO:0030163
GO:0031410
GO:0031647
GO:0034765
GO:0042391
GO:0043161
GO:0043226
GO:0044325
GO:0045732
GO:0048814
GO:0051649
GO:0060306
GO:0061630
GO:0070936
GO:0086005
GO:0098772
GO:0098794
GO:0098978
GO:0099149
GO:0140096
GO:0140252
GO:1901380
GO:1902305
GO:1902306
GO:1903861
GO:2000009
GO:2000810
GO:2001288
ILMN_1243947
ILMN_1252927
ILMN_2604457
ILMN_2878501
Msa.13432.0_s_at
Msa.20085.0_s_at
mMC023436
mMR030274
Participates
as an output of
NEDD4L ubiquitinates SMAD2/3 (Mus musculus)
as an input of
NEDD4L binds phosphorylated linker region of SMAD2/3 (Mus musculus)
as a component of
p-T-2S-SMAD2,3:SMAD4:NEDDL4 [nucleoplasm] (Mus musculus)
Other forms of this molecule
Nedd4l [cytosol]
Inferred From
NEDD4L [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSMUSP00000158044
,
ENSMUST00000237410
IntEnz
2.3.2.36
PRO
Q8CFI0
GlyGen
Q8CFI0
MGI
1933754
PDB
1WR7
,
1WR4
,
1WR3
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Z2S7-3 TSC22D3
0.524
2
UniProt:Q99N57
11
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-MMU-5672664)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-MMU-5672665)
phospho-p-S621-RAF1 [cytosol]
(R-MMU-206028)
phospho-p-Y-RAF1 [cytosol]
(R-MMU-9732747)
RAF1 [cytosol]
(R-MMU-167205)
phospho-p-S259,S621-RAF1 [cytosol]
(R-MMU-109786)
phospho-p-Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-MMU-5675420)
phospho-p-S621-RAF1 [plasma membrane]
(R-MMU-206222)
phospho-hyperphosphorylated RAF1 [plasma membrane]
(R-MMU-5675193)
phospho-p-S338-RAF1 [cytosol]
(R-MMU-5624469)
phospho-p-S338,Y340,Y341-RAF1 [cytosol]
(R-MMU-5624465)
0.524
2
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