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Caspase-3 tetramer [cytosol]
Stable Identifier
R-MMU-2534153
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Other interleukin signaling (Mus musculus)
Caspase-3 cleaves pro-interleukin-16 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Apoptotic execution phase (Mus musculus)
Apoptosis induced DNA fragmentation (Mus musculus)
Translocation of caspase-3 to the nucleus (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Apoptotic cleavage of cellular proteins (Mus musculus)
Apoptotic cleavage of cell adhesion proteins (Mus musculus)
Caspase mediated cleavage of beta-catenin (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Desmoglein 1 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Desmoglein 2 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Desmoglein 3 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Desmoplakin (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of E-Cadherin (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of TJP1 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Z0-2 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of occludin (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of plakophilin-1 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase 3-mediated cleavage of PKC delta (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase mediated cleavage of APC (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase mediated cleavage of C-IAP1 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Acinus (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Etk (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of MASK (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of MST3 (Mus musculus)
Caspase-3, Caspase-7 [cytosol] (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of PKC theta (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Rock-1 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of cytoskeletal proteins (Mus musculus)
Caspase mediated cleavage of HIP-55 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase mediated cleavage of alpha-II-Fodrin (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of GAS2 (Mus musculus)
Caspase-3, Caspase-7 [cytosol] (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of Tau (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of alpha adducin (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of gelsolin (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of vimentin at DSVD (85) (Mus musculus)
Caspase-3, Caspase-7 [cytosol] (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase activation via extrinsic apoptotic signalling pathway (Mus musculus)
Caspase activation via Dependence Receptors in the absence of ligand (Mus musculus)
Activation of caspase-3 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Caspase cleavage of DCC (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Intrinsic Pathway for Apoptosis (Mus musculus)
Apoptotic factor-mediated response (Mus musculus)
Cytochrome c-mediated apoptotic response (Mus musculus)
Activation of caspases through apoptosome-mediated cleavage (Mus musculus)
Cleavage of Procaspase-3 by the apoptosome (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
SMAC, XIAP-regulated apoptotic response (Mus musculus)
XIAP binds CASP3 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
DIABLO:XIAP:Caspase-3 [cytosol] (Mus musculus)
XIAP:Caspase-3 [cytosol] (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
XIAP:Caspase-3 [cytosol] (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Regulated Necrosis (Mus musculus)
Pyroptosis (Mus musculus)
CASP1 cleaves GSDMD (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
CASP3 cleaves GSDMD (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
CASP3 cleaves GSDME (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
CASP4, CASP5 cleave GSDMD (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
p75 NTR receptor-mediated signalling (Mus musculus)
Cell death signalling via NRAGE, NRIF and NADE (Mus musculus)
NADE modulates death signalling (Mus musculus)
p75NTR:NADE promotes caspase2/3 activation (Mus musculus)
Active Caspases 2, 3 [cytosol] (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Signaling by Hippo (Mus musculus)
Cleavage of p-STK3 (p-MST2) by caspase 3 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Cleavage of p-STK4 (p-MST1) by caspase 3 (Mus musculus)
Caspase-3 tetramer [cytosol] (Mus musculus)
Participants
components
x 2
Caspase-3 dimer [cytosol]
(Mus musculus)
Participates
as a member of
Active Caspases 2, 3 [cytosol] (Mus musculus)
Caspase-3, Caspase-7 [cytosol] (Mus musculus)
as an input of
XIAP binds CASP3 (Mus musculus)
Translocation of caspase-3 to the nucleus (Mus musculus)
as an output of
Cleavage of Procaspase-3 by the apoptosome (Mus musculus)
Activation of caspase-3 (Mus musculus)
as a component of
XIAP:Caspase-3 [cytosol] (Mus musculus)
This entity regulates
Negatively
CASP4, CASP5 cleave GSDMD
(Mus musculus)
CASP1 cleaves GSDMD
(Mus musculus)
Inferred From
Caspase-3 [cytosol]
(Homo sapiens)
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