Reactome | Lmna [nucleoplasm]

Lmna [nucleoplasm]

Stable Identifier

R-MMU-264872

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

Lamin C, P48678

Locations in the PathwayBrowser

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Cell Cycle (Mus musculus)

- Cell Cycle, Mitotic (Mus musculus)
  - M Phase (Mus musculus)
    - Mitotic Metaphase and Anaphase (Mus musculus)
      - Mitotic Anaphase (Mus musculus)
        
        Nuclear Envelope (NE) Reassembly (Mus musculus)
        
        Initiation of Nuclear Envelope (NE) Reformation (Mus musculus)
        
        BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Mus musculus)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Mus musculus)
        
        Lamin filaments [nucleoplasm] (Mus musculus)
        
        Lamin dimers [nucleoplasm] (Mus musculus)
        
        Lamin C dimer [nucleoplasm] (Mus musculus)
        
        Lmna [nucleoplasm] (Mus musculus)
    - Mitotic Prophase (Mus musculus)
      - Nuclear Envelope Breakdown (Mus musculus)
        
        Depolymerization of the Nuclear Lamina (Mus musculus)
        
        Depolymerization of lamin filaments after PKC-mediated phosphorylation (Mus musculus)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments [nuclear envelope] (Mus musculus)
        
        Lamin filaments [nucleoplasm] (Mus musculus)
        
        Lamin dimers [nucleoplasm] (Mus musculus)
        
        Lamin C dimer [nucleoplasm] (Mus musculus)
        
        Lmna [nucleoplasm] (Mus musculus)
        
        VRK1/VRK2 phosphorylate BANF1 (Mus musculus)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments [nuclear envelope] (Mus musculus)
        
        Lamin filaments [nucleoplasm] (Mus musculus)
        
        Lamin dimers [nucleoplasm] (Mus musculus)
        
        Lamin C dimer [nucleoplasm] (Mus musculus)
        
        Lmna [nucleoplasm] (Mus musculus)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Mus musculus)
        
        Lamin filaments [nucleoplasm] (Mus musculus)
        
        Lamin dimers [nucleoplasm] (Mus musculus)
        
        Lamin C dimer [nucleoplasm] (Mus musculus)
        
        Lmna [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:P48678-1 Lmna

Gene Names

Lmna, Lmn1

Participates

as a component of

Lamin C dimer [nucleoplasm] (Mus musculus)

Other forms of this molecule

p-S22,S392-Lmna-1 [nucleoplasm]

Lmna-1 [nucleoplasm]

phospho-Lmna [nucleoplasm]

Lmna [cytosol]

Lmna [nuclear envelope]

Lmna [nucleoplasm]

Inferred From

Lamin C [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_062263.1, NP_001002011.2, NP_001104572.1, XP_006501136.1

ENSEMBL

ENSMUSP00000113093, ENSMUST00000036252, ENSMUST00000120377, ENSMUSP00000040265, ENSMUST00000029699, ENSMUSP00000029699, ENSMUSG00000028063

PRO

P48678

GlyGen

P48678

MGI

96794

PDB

1UFG

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31750 Akt1	12	phospho-Akt1 [nucleoplasm] (R-MMU-198357) phospho-Akt1 [cytosol] (R-MMU-198356) phospho-Akt1 [plasma membrane] (R-MMU-377265) Akt1 [plasma membrane] (R-MMU-199416) Akt1 [cytosol] (R-MMU-58252) phospho-Akt1 [cytosol] (R-MMU-198634) phospho-Akt1 [cytosol] (R-MMU-8848757) p-T308,S473-Akt1 [cytosol] (R-MMU-162346) phospho-Akt1 [plasma membrane] (R-MMU-199430) Akt1 [cytosol] (R-MMU-189709) phospho-Akt1 [cytosol] (R-MMU-9841264) p-T308,S473-Akt1 [plasma membrane] (R-MMU-1445123)	0.564	2

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