Reactome | Lmna [nucleoplasm]

Lmna [nucleoplasm]

Stable Identifier

R-MMU-264872

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

Lamin C, P48678

Locations in the PathwayBrowser

Expand all

Cell Cycle (Mus musculus)

- Cell Cycle, Mitotic (Mus musculus)
  - M Phase (Mus musculus)
    - Mitotic Prophase (Mus musculus)
      - Nuclear Envelope Breakdown (Mus musculus)
        
        Depolymerisation of the Nuclear Lamina (Mus musculus)
        
        Depolymerization of lamin filaments after PKC-mediated phosphorylation (Mus musculus)
        
        EMD/TMPO/LEMD3/LEMD2:Lamin filaments [nuclear envelope] (Mus musculus)
        
        Lamin filaments [nucleoplasm] (Mus musculus)
        
        Lamin dimers [nucleoplasm] (Mus musculus)
        
        Lamin C dimer [nucleoplasm] (Mus musculus)
        
        Lmna [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:P48678 Lmna

Gene Names

Lmna, Lmn1

Chain

chain:1-662, chain:1-647, propeptide:648-662, propeptide:663-665

Reference Genes

BioGPS Gene:16905 Lmna

ENSEMBL:ENSMUSG00000028063 Lmna

KEGG Gene (Mus musculus):16905 Lmna

Monarch:16905 Lmna

NCBI Gene:16905 Lmna

UCSC:P48678 Lmna

Reference Transcript

Other Identifiers

10499394

1421654_a_at

1425472_a_at

1457670_s_at

16905

17406783

4307703

4445885

4479405

4524756

4584993

4687050

4817758

4828760

4878601

4938777

5039122

5114835

5162232

5214105

5316587

5350783

5387647

5510638

5549630

98059_s_at

98060_at

A_51_P313561

A_51_P313566

A_52_P137765

GE37391

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005635

GO:0005638

GO:0005652

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0005856

GO:0005882

GO:0006259

GO:0006464

GO:0006606

GO:0006810

GO:0006913

GO:0006950

GO:0006997

GO:0006998

GO:0007005

GO:0007010

GO:0007049

GO:0007165

GO:0007517

GO:0007568

GO:0008150

GO:0008157

GO:0008219

GO:0008283

GO:0008285

GO:0010628

GO:0015031

GO:0016363

GO:0016604

GO:0016607

GO:0019899

GO:0030010

GO:0030154

GO:0030334

GO:0030951

GO:0031647

GO:0031965

GO:0032204

GO:0034504

GO:0034613

GO:0034641

GO:0035861

GO:0040011

GO:0042592

GO:0042802

GO:0043226

GO:0045669

GO:0048471

GO:0048856

GO:0048870

GO:0051276

GO:0055015

GO:0061024

GO:0071456

GO:0072201

GO:0090201

GO:0090343

GO:1900114

GO:1900180

GO:1903243

GO:1904178

GO:1990683

GO:2001237

ILMN_1221646

ILMN_1254405

ILMN_1255510

ILMN_2662387

ILMN_3121891

d49733-3_s_at

mMC016894

mMC023449

Participates

as a component of

Lamin C dimer [nucleoplasm] (Mus musculus)

Other forms of this molecule

Lmna [nuclear envelope]

phospho-Lmna [nucleoplasm]

Lmna [nucleoplasm]

Inferred From

Lamin C [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001104572.1, NP_001002011.2, NP_062263.1, XP_006501136.1

Ensembl

ENSMUST00000120377, ENSMUSP00000113093, ENSMUSP00000040265, ENSMUST00000036252, ENSMUSG00000028063, ENSMUSP00000029699, ENSMUST00000029699

PRO

P48678

MGI

96794

PDB

1UFG

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31750 Akt1	10	phospho-Akt1 [cytosol] (R-MMU-8848757) p-T308,S473-Akt1 [cytosol] (R-MMU-162346) phospho-Akt1 [plasma membrane] (R-MMU-377265) phospho-Akt1 [cytosol] (R-MMU-198356) p-T308,S473-Akt1 [plasma membrane] (R-MMU-1445123) phospho-Akt1 [plasma membrane] (R-MMU-199430) Akt1 [cytosol] (R-MMU-58252) phospho-Akt1 [cytosol] (R-MMU-198634) phospho-Akt1 [nucleoplasm] (R-MMU-198357) Akt1 [plasma membrane] (R-MMU-199416)	0.564	2
UniProt:Q5FW52 MLIP			0.488	2