Reactome | Efna3 [plasma membrane]

Efna3 [plasma membrane]

Stable Identifier

R-MMU-2682324

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

EFNA3, O08545

Locations in the PathwayBrowser

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Developmental Biology (Mus musculus)

- Nervous system development (Mus musculus)
  - Axon guidance (Mus musculus)
    - EPH-Ephrin signaling (Mus musculus)
      - EPH receptors autophosphorylate (Mus musculus)
        
        EPH-ephrin oligomers [plasma membrane] (Mus musculus)
        
        EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
      - EPH-ephrin mediated repulsion of cells (Mus musculus)
        
        EPHA binds TIAM1 (Mus musculus)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Mus musculus)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        SFKs phosphorylate VAV2,3 (Mus musculus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        TIAM1 exchanges GTP for GDP on RAC1, activating it (Mus musculus)
        
        EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Mus musculus)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        VAV exchanges GTP for GDP on RAC1, activating it (Mus musculus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        p-EPHs bind VAV2,3 (Mus musculus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Mus musculus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
      - EPH:EFN dimers tetramerise (Mus musculus)
        
        EPH-EFN dimers [plasma membrane] (Mus musculus)
        
        EPHA:EFNA dimers [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
      - EPH:EFN tetramers oligomerise (Mus musculus)
        
        EPH-EFN dimers [plasma membrane] (Mus musculus)
        
        EPHA:EFNA dimers [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        EPH-ephrin oligomers [plasma membrane] (Mus musculus)
        
        EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
      - EPHA-mediated growth cone collapse (Mus musculus)
        
        NGEF exchanges GTP for GDP on RHOA (Mus musculus)
        
        EFNAs:p-EPHAs:SFKs:p-Y179-NGEF [plasma membrane] (Mus musculus)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Mus musculus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Mus musculus)
        
        p-EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
      - EPHAs bind EFNAs (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)
        
        EPHAs:EFNAs [plasma membrane] (Mus musculus)
        
        EFNAs [plasma membrane] (Mus musculus)
        
        Efna3 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:O08545

Gene Names

Efna3

Reference Genes

BioGPS Gene:13638 Efna3

ENSEMBL:ENSMUSG00000028039

ENSEMBL:ENSMUSG00000028039.12 Efna3

KEGG Gene (Mus musculus):13638 Efna3

Monarch:13638 Efna3

NCBI Gene:13638 Efna3

UCSC:O08545 Efna3

Reference Transcript

RefSeq:NM_010108.1 Efna3

Other Identifiers

100289_at

10499545

108873_at

13638

136657_at

1431170_at

1455344_at

17407001

4455932

4457627

4512839

4571049

4742678

5489099

A_51_P186203

A_55_P2031157

A_55_P2181796

GE111018

GE130058

GO:0005886

GO:0007411

GO:0016020

GO:0016525

GO:0023052

GO:0030154

GO:0045664

GO:0046875

GO:0048013

GO:0048856

GO:0098552

ILMN_1220598

ILMN_2614731

ILMN_2818879

mMC009782

Participates

as a member of

EFNAs [plasma membrane] (Mus musculus)

Inferred From

EFNA3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_034238.1

Ensembl

ENSMUSP00000029673, ENSMUST00000029673, ENSMUSG00000028039

PRO

O08545

MGI

106644

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