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AKR1C1 [cytosol]
Stable Identifier
R-MMU-2855253
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q8VC77
Locations in the PathwayBrowser
Expand all
Drug ADME (Mus musculus)
Prednisone ADME (Mus musculus)
AKR1C1 hydrogenates PREDN,PREDL (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Arachidonic acid metabolism (Mus musculus)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Mus musculus)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
PGH2 is reduced to PGF2a by AKR1C3 (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Synthesis of bile acids and bile salts (Mus musculus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Mus musculus)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Mus musculus)
Aldo-keto reductase family [cytosol] (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Mus musculus)
Aldo-keto reductase family [cytosol] (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Mus musculus)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Mus musculus)
Aldo-keto reductase family [cytosol] (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Mus musculus)
Aldo-keto reductase family [cytosol] (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Mus musculus)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Mus musculus)
Aldo-keto reductase family [cytosol] (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Mus musculus)
Aldo-keto reductase family [cytosol] (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of fat-soluble vitamins (Mus musculus)
Retinoid metabolism and transport (Mus musculus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Mus musculus)
AKRs [cytosol] (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
Sensory Perception (Mus musculus)
Visual phototransduction (Mus musculus)
Retinoid metabolism and transport (Mus musculus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Mus musculus)
AKRs [cytosol] (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
Signaling by Retinoic Acid (Mus musculus)
RA biosynthesis pathway (Mus musculus)
AKR1C3 reduces atRAL to atROL (Mus musculus)
Homologues of AKR1C1 [cytosol] (Mus musculus)
AKR1C1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8VC77
Reference Genes
BioGPS Gene:116852
CTD Gene:116852
ENSEMBL:ENSMUSG00000054757
ENSEMBL:ENSMUSG00000054757.15
KEGG Gene (Mus musculus):116852
Monarch:116852
NCBI Gene:116852
UCSC:Q8VC77
Reference Transcript
RefSeq:NM_001311132.1
Other Identifiers
10407456
116374_at
116852
1425387_at
17290288
4418035
4690890
4799492
4939212
4984590
5260536
5348134
5508943
5517798
5518139
5564266
5604755
A_51_P382764
GE42123
GO:0001758
GO:0003824
GO:0004032
GO:0004033
GO:0004745
GO:0005634
GO:0005737
GO:0005829
GO:0006629
GO:0006693
GO:0006694
GO:0006766
GO:0007186
GO:0008284
GO:0009410
GO:0012501
GO:0016488
GO:0016491
GO:0016655
GO:0018636
GO:0023052
GO:0031406
GO:0032052
GO:0035410
GO:0042448
GO:0042574
GO:0043226
GO:0043627
GO:0044597
GO:0044598
GO:0045550
GO:0045703
GO:0047006
GO:0047020
GO:0047023
GO:0047042
GO:0047045
GO:0047086
GO:0047115
GO:0047743
GO:0047787
GO:0048385
GO:0051897
GO:0061370
GO:0071277
GO:0071379
GO:0071384
GO:0071395
GO:0071799
GO:1900053
GO:1901135
GO:2000224
GO:2000353
GO:2000379
ILMN_2483596
mMC007834
Participates
as a member of
Homologues of AKR1C1 [cytosol] (Mus musculus)
Inferred From
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001298061.1
Ensembl
ENSMUST00000080361
,
ENSMUSG00000054757
,
ENSMUSP00000079232
MGI
2151104
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