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Tsc2 [cytosol]
Stable Identifier
R-MMU-2980548
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
TSC2, Q61037
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
AKT phosphorylates TSC2, inhibiting it (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
Formation of TSC1:TSC2 complex (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
AKT phosphorylates targets in the cytosol (Mus musculus)
AKT phosphorylates TSC2, inhibiting it (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
MTOR signalling (Mus musculus)
Energy dependent regulation of mTOR by LKB1-AMPK (Mus musculus)
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
Inhibition of TSC complex formation by PKB (Mus musculus)
Phosphorylation of TSC2 by PKB (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
Phosphorylation of complexed TSC2 by PKB (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Rab regulation of trafficking (Mus musculus)
TBC/RABGAPs (Mus musculus)
TBC1D7 binds the TSC1-TSC2 complex (Mus musculus)
TBC1D7:TSC1:TSC2 [cytosol] (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
TSC1:TSC2 [cytosol] (Mus musculus)
Tsc2 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q61037
Gene Names
Tsc2
Reference Genes
ENSEMBL:ENSMUSG00000002496
UCSC:Q61037 Tsc2
Participates
as an input of
Phosphorylation of TSC2 by PKB (Mus musculus)
AKT phosphorylates TSC2, inhibiting it (Mus musculus)
Formation of TSC1:TSC2 complex (Mus musculus)
as a component of
TSC1:TSC2 [cytosol] (Mus musculus)
Other forms of this molecule
phospho-Tsc2 [cytosol]
phospho-Tsc2 [cytosol]
phospho-Tsc2 [cytosol]
Inferred From
TSC2 [cytosol]
(Homo sapiens)
Cross References
PRO
Q61037
MGI
102548
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9EP53
2
Tsc1 [plasma membrane]
(R-MMU-165169)
Tsc1 [cytosol]
(R-MMU-5672338)
0.623
6
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