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Pik3r1 [cytosol]
Stable Identifier
R-MMU-3080572
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
K63polyUb-PIK3R1, P26450
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Mus musculus)
Regulation of signaling by CBL (Mus musculus)
CBL ubiquitinates PI3K (Mus musculus)
FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks [cytosol] (Mus musculus)
K63polyUb-p85-containing Class 1A PI3Ks [cytosol] (Mus musculus)
K63polyUb-PI3K alpha [cytosol] (Mus musculus)
K63polyUb-PI3K-regulatory subunits [cytosol] (Mus musculus)
Pik3r1 [cytosol] (Mus musculus)
K63polyUb-PI3K beta [cytosol] (Mus musculus)
K63polyUb-PI3K-regulatory subunits [cytosol] (Mus musculus)
Pik3r1 [cytosol] (Mus musculus)
K63polyUb-PI3K delta [cytosol] (Mus musculus)
K63polyUb-PI3K-regulatory subunits [cytosol] (Mus musculus)
Pik3r1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P26450 Pik3r1
Gene Names
Pik3r1
Chain
initiator methionine:, chain:2-724
Reference Genes
BioGPS Gene:18708 Pik3r1
KEGG:mmu:18708 Pik3r1
Monarch:18708 Pik3r1
NCBI Gene:18708 Pik3r1
UCSC:P26450 Pik3r1
Reference Transcript
RefSeq:NM_001077495.2 Pik3r1
Other Identifiers
10411782
113019_at
129853_at
1425514_at
1425515_at
1438682_at
1451737_at
163548_at
17295796
18708
4488390
4509795
4574844
4575869
4582656
4584747
4592987
4627475
4630640
4660240
4670222
4670693
4701241
4723068
4754477
4792657
4803871
4813365
4944558
4982251
5041143
5093192
5109065
5110986
5173919
5189942
5214469
5293013
5338577
5385180
5432805
5450486
5452837
5486662
5491218
5519462
5614602
96592_at
A_51_P511236
A_52_P235476
A_52_P307938
A_52_P407239
GE1396611
GE33132
GO:0001678
GO:0001784
GO:0001934
GO:0001953
GO:0002376
GO:0002687
GO:0003824
GO:0005102
GO:0005158
GO:0005159
GO:0005161
GO:0005168
GO:0005515
GO:0005516
GO:0005634
GO:0005737
GO:0005801
GO:0005829
GO:0005911
GO:0005942
GO:0005943
GO:0005975
GO:0006006
GO:0006351
GO:0006355
GO:0006366
GO:0006606
GO:0006629
GO:0006886
GO:0006913
GO:0007162
GO:0007165
GO:0008286
GO:0008625
GO:0008630
GO:0010459
GO:0010592
GO:0010628
GO:0010656
GO:0015031
GO:0016020
GO:0016301
GO:0016303
GO:0016740
GO:0019209
GO:0019221
GO:0019901
GO:0019903
GO:0019904
GO:0022408
GO:0030154
GO:0030183
GO:0030316
GO:0030331
GO:0030335
GO:0030971
GO:0031625
GO:0032760
GO:0032868
GO:0032869
GO:0032991
GO:0033120
GO:0034143
GO:0034644
GO:0034976
GO:0035014
GO:0035655
GO:0036092
GO:0036312
GO:0042267
GO:0042307
GO:0043066
GO:0043125
GO:0043226
GO:0043491
GO:0043559
GO:0043560
GO:0045663
GO:0045671
GO:0045776
GO:0045861
GO:0045944
GO:0046488
GO:0046854
GO:0046935
GO:0046982
GO:0048009
GO:0048471
GO:0048661
GO:0048662
GO:0048870
GO:0050821
GO:0051117
GO:0051219
GO:0051384
GO:0051491
GO:0051492
GO:0051497
GO:0051591
GO:0051965
GO:0060396
GO:0097529
GO:0098542
GO:0098772
GO:0120183
GO:1900103
GO:1903076
GO:1990578
ILMN_1249335
ILMN_1259124
ILMN_2473531
ILMN_2726359
ILMN_3040050
ILMN_3114641
mMR026375
u50413_s_at
Participates
as a member of
K63polyUb-PI3K-regulatory subunits [cytosol] (Mus musculus)
Other forms of this molecule
p-Y-Pik3r1 [cytosol]
Pi3k-p85 alpha [cytosol]
Pik3r1 [cytosol]
Pik3r1 [plasma membrane]
Inferred From
K63polyUb-PIK3R1 [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K63-polyubiquitin [cytosol]) at unknown position
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_001070963.1
ENSEMBL
ENSMUST00000055518
,
ENSMUSP00000056774
PRO
P26450
GlyGen
P26450
MGI
97583
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35569 Irs1
8
p-Irs1 [cytosol]
(R-MMU-2671869)
phospho-Irs1 [plasma membrane]
(R-MMU-2445090)
Irs1 [plasma membrane]
(R-MMU-2425392)
Phospho-IRS1 (by NTRK1) [cytosol]
(R-MMU-198285)
Irs1 [cytosol]
(R-MMU-198257)
Irs1 [cytosol]
(R-MMU-74769)
phospho-Irs1 [cytosol]
(R-MMU-74772)
phospho-Irs1 [plasma membrane]
(R-MMU-198366)
0.702
3
UniProt:P42337 Pik3ca
1
Pik3ca [cytosol]
(R-MMU-9027214)
0.573
7
UniProt:Q8BTI9 Pik3cb
2
Pik3cb [cytosol]
(R-MMU-9027217)
Pik3cb [cytosol]
(R-MMU-74788)
0.573
5
UniProt:Q8IZP0 ABI1
2
p-5S-ABI1 [cytosol]
(R-HSA-2029034)
ABI1 [cytosol]
(R-HSA-1671643)
0.524
3
UniProt:Q8R5H6
3
phospho-Wasf1 [cytosol]
(R-MMU-5672390)
phospho-Wasf1 [cytosol]
(R-MMU-2029058)
Wasf1 [cytosol]
(R-MMU-200965)
0.499
2
UniProt:Q9WVS0
2
Icos [plasma membrane]
(R-MMU-198144)
phospho-Icos [plasma membrane]
(R-MMU-389927)
0.499
2
UniProt:Q7TMB8
5
Cyfip1 [tertiary granule lumen]
(R-MMU-6800176)
Cyfip1 [secretory granule lumen]
(R-MMU-6800940)
Cyfip1 [extracellular region]
(R-MMU-6800473)
Cyfip1 [specific granule lumen]
(R-MMU-6800167)
Cyfip1 [cytosol]
(R-MMU-5672575)
0.462
2
UniProt:P28660
1
Nckap1 [cytosol]
(R-MMU-200979)
0.462
2
UniProt:P22681 CBL
20
PolyUb,p-Y-CBL [cytosol]
(R-HSA-9763893)
CBL R420G [cytosol]
(R-HSA-9706203)
CBL R420Q [cytosol]
(R-HSA-9706186)
CBL Y371H [cytosol]
(R-HSA-9706680)
CBL H398Y [cytosol]
(R-HSA-9706639)
CBL P417A [cytosol]
(R-HSA-9706636)
CBL S376F [cytosol]
(R-HSA-9706643)
CBL E366_Q409del [cytosol]
(R-HSA-9706179)
CBL del366-477 [cytosol]
(R-HSA-9706176)
CBL R499L [cytosol]
(R-HSA-9706678)
CBL L380P [cytosol]
(R-HSA-9706630)
CBL L287R [cytosol]
(R-HSA-9706693)
CBL L380R [cytosol]
(R-HSA-9706635)
CBL G375P [cytosol]
(R-HSA-9706219)
CBL P417L [cytosol]
(R-HSA-9706634)
CBL H398Q [cytosol]
(R-HSA-9706633)
CBL P417R [cytosol]
(R-HSA-9706632)
CBL [cytosol]
(R-HSA-112199)
p-Y371-CBL [cytosol]
(R-HSA-182940)
p-Y700,Y731,Y774-CBL [cytosol]
(R-HSA-912656)
0.462
2
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