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PolyUb-TP53 Tetramer [nucleoplasm]
Stable Identifier
R-MMU-3209186
Type
Complex
Species
Mus musculus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G1/S DNA Damage Checkpoints (Mus musculus)
p53-Dependent G1/S DNA damage checkpoint (Mus musculus)
p53-Dependent G1 DNA Damage Response (Mus musculus)
Stabilization of p53 (Mus musculus)
MDM2 ubiquitinates TP53 (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
Ubiquitinated TP53 translocates to the cytosol (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
G2/M Checkpoints (Mus musculus)
GTSE1 binds TP53 (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
GTSE1 promotes translocation of TP53 to the cytosol (Mus musculus)
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Mus musculus)
GTSE1 binds TP53 (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
GTSE1 promotes translocation of TP53 to the cytosol (Mus musculus)
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular Senescence (Mus musculus)
Oncogene Induced Senescence (Mus musculus)
MDM2 ubiquitinates TP53 (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
Oxidative Stress Induced Senescence (Mus musculus)
MDM2 ubiquitinates TP53 (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
Regulation of TP53 Activity (Mus musculus)
Regulation of TP53 Expression and Degradation (Mus musculus)
Regulation of TP53 Degradation (Mus musculus)
MDM2 ubiquitinates TP53 (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
USP7 deubiquitinates TP53 and counteracts MDM2 (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
Ubiquitinated TP53 translocates to the cytosol (Mus musculus)
PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 4
PolyUb-TP53 [nucleoplasm]
(Mus musculus)
Participates
as an input of
USP7 deubiquitinates TP53 and counteracts MDM2 (Mus musculus)
Ubiquitinated TP53 translocates to the cytosol (Mus musculus)
GTSE1 binds TP53 (Mus musculus)
as an output of
MDM2 ubiquitinates TP53 (Mus musculus)
as a component of
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Mus musculus)
Inferred From
PolyUb-TP53 Tetramer [nucleoplasm]
(Homo sapiens)
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