Reactome | Lef1 [nucleoplasm]

Lef1 [nucleoplasm]

Stable Identifier

R-MMU-3214972

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

LEF1, P27782

Locations in the PathwayBrowser

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Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional regulation by RUNX3 (Mus musculus)
      - RUNX3 regulates WNT signaling (Mus musculus)
        
        RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Mus musculus)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        Lef1 [nucleoplasm] (Mus musculus)
        
        RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Mus musculus)
        
        Lef1 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:P27782 Lef1

Gene Names

Lef1

Chain

chain:1-397

Reference Genes

BioGPS Gene:16842 Lef1

ENSEMBL:ENSMUSG00000027985.15 Lef1

KEGG Gene (Mus musculus):16842 Lef1

Monarch:16842 Lef1

NCBI Gene:16842 Lef1

UCSC:P27782 Lef1

Reference Transcript

RefSeq:NM_010703.4 Lef1

Other Identifiers

103628_at

103629_g_at

10496091

111398_at

1421299_a_at

1454734_at

16842

17402662

4364231

4364478

4366349

4425495

4500947

4551281

4559891

4585358

4585876

4593025

4739804

4890014

4894810

4936262

4941061

5095279

5135695

5136840

5165208

5209661

5252996

5260900

5304528

5322729

5403785

5415491

5463846

5537741

5550224

5580535

5602831

A_51_P420400

A_51_P501145

A_55_P2076871

GE1515806

GO:0000122

GO:0000976

GO:0000977

GO:0000978

GO:0000981

GO:0000987

GO:0001222

GO:0001227

GO:0001228

GO:0001569

GO:0001649

GO:0001756

GO:0001837

GO:0001944

GO:0002040

GO:0002376

GO:0003676

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005737

GO:0006310

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0007155

GO:0008013

GO:0008301

GO:0009888

GO:0010628

GO:0010718

GO:0012501

GO:0016055

GO:0021542

GO:0021766

GO:0021861

GO:0021873

GO:0021943

GO:0022407

GO:0023052

GO:0030111

GO:0030154

GO:0030177

GO:0030223

GO:0030326

GO:0030331

GO:0030335

GO:0030509

GO:0030854

GO:0030879

GO:0032696

GO:0032713

GO:0032714

GO:0032993

GO:0033153

GO:0042100

GO:0042393

GO:0042475

GO:0042826

GO:0043066

GO:0043226

GO:0043565

GO:0043586

GO:0043923

GO:0045063

GO:0045295

GO:0045588

GO:0045597

GO:0045843

GO:0045892

GO:0045893

GO:0045944

GO:0046632

GO:0048341

GO:0048468

GO:0048513

GO:0048856

GO:0048870

GO:0050767

GO:0050877

GO:0050909

GO:0060033

GO:0060070

GO:0060325

GO:0060326

GO:0060561

GO:0060710

GO:0061153

GO:0062009

GO:0070016

GO:0070742

GO:0071168

GO:0071345

GO:0071353

GO:0071864

GO:0071866

GO:0071895

GO:0090068

GO:0090575

GO:0098772

GO:0140110

GO:0140416

GO:1901331

GO:1902262

GO:1902732

GO:1904019

GO:1990837

GO:1990907

ILMN_1231087

ILMN_1239469

ILMN_2648475

Msa.158.0_s_at

mMC007996

mMC022116

x58636_s_at

Participates

as a member of

as a candidate of

Other forms of this molecule

Lef1 [nucleoplasm]

phospho-Lef1 [nucleoplasm]

Inferred From

LEF1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_034833.2

Ensembl

ENSMUSP00000029611, ENSMUST00000029611, ENSMUSG00000027985

PRO

P27782

MGI

96770

PDB

3OUW, 2LEF, 3OUX

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