Reactome | Tas2r136 [plasma membrane]

Tas2r136 [plasma membrane]

Stable Identifier

R-MMU-3299626-2

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

TAS2R30, Q7TQA8

Locations in the PathwayBrowser

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Sensory Perception (Mus musculus)

- Sensory perception of taste (Mus musculus)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
    - Bitter compound binds bitter taste receptor (TAS2R) (Mus musculus)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS2R (non-orphan) [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Mus musculus)
        
        TAS2R30:ligand [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
      - T2Rs bind bitter-tasting compounds (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R30 [plasma membrane] (Mus musculus)
        
        Tas2r136 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q7TQA8

Gene Names

Tas2r136

Reference Genes

BioGPS Gene:353165 Tas2r136

CTD Gene:353165 Tas2r136

ENSEMBL:ENSMUSG00000053217

KEGG Gene (Mus musculus):353165 Tas2r136

Monarch:353165 Tas2r136

NCBI Gene:353165 Tas2r136

UCSC:Q7TQA8 Tas2r136

Reference Transcript

RefSeq:NM_181276.1 Tas2r136

Participates

as a member of

Homologues of TAS2R30 [plasma membrane] (Mus musculus)

Other forms of this molecule

Tas2r136 [plasma membrane]

Inferred From

TAS2R30 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_851793.1

PRO

Q7TQA8

MGI

2681304

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