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Casp8 [mitochondrial outer membrane]
Stable Identifier
R-MMU-351828
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
mitochondrial outer membrane
Synonyms
CASP8(385-479), O89110
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Apoptotic execution phase (Mus musculus)
Apoptotic cleavage of cellular proteins (Mus musculus)
Caspase mediated cleavage of BAP31 (Mus musculus)
active caspase-8 [mitochondrial outer membrane] (Mus musculus)
Caspase-8 dimer [mitochondrial outer membrane] (Mus musculus)
Casp8 [mitochondrial outer membrane] (Mus musculus)
Translocation of active caspase-8 to the mitochondrial membrane (Mus musculus)
active caspase-8 [mitochondrial outer membrane] (Mus musculus)
Caspase-8 dimer [mitochondrial outer membrane] (Mus musculus)
Casp8 [mitochondrial outer membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:O89110
Gene Names
Casp8
Reference Genes
BioGPS Gene:12370 Casp8
ENSEMBL:ENSMUSG00000026029
ENSEMBL:ENSMUSG00000026029.15 Casp8
KEGG Gene (Mus musculus):12370 Casp8
Monarch:12370 Casp8
NCBI Gene:12370 Casp8
UCSC:O89110 Casp8
Reference Transcript
RefSeq:NM_009812.2 Casp8
RefSeq:NM_001080126.1 Casp8
RefSeq:NM_001277926.1 Casp8
Other Identifiers
102328_at
10346564
12370
1424552_at
17213213
4414187
4466287
4605085
4746757
4857306
5020777
5033743
5086615
5215711
5464876
5566874
5567361
A_51_P247799
GE41643
GO:0001525
GO:0001817
GO:0001841
GO:0002376
GO:0003824
GO:0004175
GO:0004197
GO:0005123
GO:0005164
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005829
GO:0005886
GO:0006508
GO:0006915
GO:0007507
GO:0008233
GO:0008234
GO:0008625
GO:0008656
GO:0012501
GO:0016485
GO:0016787
GO:0023052
GO:0030154
GO:0030163
GO:0030225
GO:0030690
GO:0031264
GO:0031265
GO:0031625
GO:0032731
GO:0032991
GO:0034612
GO:0035877
GO:0036462
GO:0042802
GO:0042981
GO:0043065
GO:0043123
GO:0043124
GO:0043226
GO:0043525
GO:0044297
GO:0044877
GO:0045088
GO:0045471
GO:0045651
GO:0045862
GO:0048738
GO:0048856
GO:0051603
GO:0051604
GO:0060546
GO:0070243
GO:0070266
GO:0070269
GO:0097110
GO:0097153
GO:0097190
GO:0097191
GO:0097194
GO:0097199
GO:0097264
GO:0097284
GO:0097342
GO:0098542
GO:0098772
GO:0140096
GO:1900119
GO:2001233
GO:2001238
ILMN_1243876
ILMN_3097868
Msa.28381.0_s_at
mMC023356
Participates
as a component of
Caspase-8 dimer [mitochondrial outer membrane] (Mus musculus)
Other forms of this molecule
Casp8 [cytosol]
Casp8 [mitochondrial outer membrane]
Casp8 [cytosol]
Casp8 [cytosol]
Casp8 [cytosol]
Inferred From
CASP8(385-479) [mitochondrial outer membrane]
(Homo sapiens)
Cross References
RefSeq
NP_033942.1
,
NP_001073595.1
,
NP_001264855.1
IntEnz
3.4.22.61
Ensembl
ENSMUST00000027189
,
ENSMUSP00000127375
,
ENSMUSG00000026029
,
ENSMUSP00000027189
,
ENSMUST00000165549
PRO
O89110
MGI
1261423
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q61160
1
Fadd [cytosol]
(R-MMU-54639)
0.813
6
UniProt:P25446
1
Fas [plasma membrane]
(R-MMU-66248)
0.669
3
UniProt:Q9D8Y7
1
Tnfaip8l2 [cytosol]
(R-MMU-8874472)
0.524
2
UniProt:P01375 TNF
5
TNF(52-76) [extracellular region]
(R-HSA-8863375)
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-233) [plasma membrane]
(R-HSA-66220)
0.499
2
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