Reactome | Nmbr [plasma membrane]

Nmbr [plasma membrane]

Stable Identifier

R-MMU-375357

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

NMBR, O54799

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Nmbr [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Nmbr [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Nmbr [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Nmbr [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Nmbr [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Nmbr [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Bombesin-like receptors bind bombesin homologues (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Nmbr [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Nmbr [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:O54799

Gene Names

Nmbr

Reference Genes

BioGPS Gene:18101 Nmbr

ENSEMBL:ENSMUSG00000019865

ENSEMBL:ENSMUSG00000019865.10 Nmbr

KEGG Gene (Mus musculus):18101 Nmbr

Monarch:18101 Nmbr

NCBI Gene:18101 Nmbr

UCSC:O54799 Nmbr

Reference Transcript

RefSeq:NM_008703.2 Nmbr

Other Identifiers

101726_at

10361818

1422342_at

1438885_at

17231774

18101

4407648

4482755

4989940

5028452

5085247

5182140

5197065

5232853

5434122

69412

A_51_P396272

A_55_P2012794

GE34102

GO:0002376

GO:0004930

GO:0004946

GO:0005829

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008188

GO:0008528

GO:0016020

GO:0023052

GO:0031989

GO:0032715

GO:0032727

GO:0060089

GO:0090290

GO:0098542

GO:0140374

GO:0160023

GO:1903942

ILMN_2662901

mMC020448

Participates

as a member of

Bombesin-like receptor [plasma membrane] (Mus musculus)

Inferred From

NMBR [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032729.1

Ensembl

ENSMUST00000020015, ENSMUSG00000019865, ENSMUSP00000020015

PRO

O54799

MGI

1100525