Reactome | Grpr [plasma membrane]

Grpr [plasma membrane]

Stable Identifier

R-MMU-375363

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

GRPR, P21729

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Grpr [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Grpr [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Grpr [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Grpr [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Grpr [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Grpr [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Bombesin-like receptors bind bombesin homologues (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Grpr [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Mus musculus)
        
        Bombesin-like receptor [plasma membrane] (Mus musculus)
        
        Grpr [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P21729

Gene Names

Grpr

Reference Genes

BioGPS Gene:14829 Grpr

ENSEMBL:ENSMUSG00000031364

ENSEMBL:ENSMUSG00000031364.3 Grpr

KEGG Gene (Mus musculus):14829 Grpr

Monarch:14829 Grpr

NCBI Gene:14829 Grpr

UCSC:P21729 Grpr

Reference Transcript

RefSeq:NM_008177.3 Grpr

Other Identifiers

10607712

1421470_at

1450260_at

14829

17545910

4411492

5075718

5170569

5380319

5531623

5555254

98781_at

A_52_P646957

GE42504

GO:0004930

GO:0004946

GO:0005515

GO:0005886

GO:0007165

GO:0007186

GO:0007200

GO:0007218

GO:0007611

GO:0008188

GO:0008528

GO:0016020

GO:0023052

GO:0031989

GO:0035176

GO:0036343

GO:0042127

GO:0042923

GO:0043207

GO:0050877

GO:0060089

GO:0061744

GO:1903942

GO:2000987

ILMN_2735717

M57922_s_at

Msa.724.0_at

mMC017829

Participates

as a member of

Bombesin-like receptor [plasma membrane] (Mus musculus)

Inferred From

GRPR [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032203.1

ZINC - Substances

GRPR_MOUSE

ZINC target

P21729

Ensembl

ENSMUSP00000033730, ENSMUSG00000031364, ENSMUST00000033730

PRO

P21729

ZINC - Predictions - Purchasable

GRPR_MOUSE

MGI

95836