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Nr1h2 [nucleoplasm]
Stable Identifier
R-MMU-375500
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
NR1H2, Q60644
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Nuclear Receptor transcription pathway (Mus musculus)
Formation of NR-MED1 Coactivator Complex (Mus musculus)
NR [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
NR-MED1 Coactivator Complex [nucleoplasm] (Mus musculus)
NR [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
Formation of NR-NCOR Corepressor Complex (Mus musculus)
NR [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
NR-NCOR CoRepressor Complex [nucleoplasm] (Mus musculus)
NR [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
SUMOylation (Mus musculus)
SUMO E3 ligases SUMOylate target proteins (Mus musculus)
SUMOylation of intracellular receptors (Mus musculus)
HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Mus musculus)
NR1H2:hydroxycholesterol [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
NR1H2 and NR1H3-mediated signaling (Mus musculus)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Mus musculus)
Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NCOR [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Mus musculus)
Co-repressor complex dissociates from the transcription unit of the ABCA1 gene (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
NCOA1 recruits EP300 to the ABCA1 promoter (Mus musculus)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] (Mus musculus)
NR1H2,3:RXR [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
Transport of small molecules (Mus musculus)
Plasma lipoprotein assembly, remodeling, and clearance (Mus musculus)
Plasma lipoprotein clearance (Mus musculus)
VLDLR internalisation and degradation (Mus musculus)
MYLIP dimer ubiquitinates VLDLR on Lys-839 (Mus musculus)
NR1H2,NR1H3 [nucleoplasm] (Mus musculus)
Nr1h2 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q60644
Gene Names
Nr1h2
Reference Genes
BioGPS Gene:22260 Nr1h2
ENSEMBL:ENSMUSG00000060601
ENSEMBL:ENSMUSG00000060601.14 Nr1h2
KEGG Gene (Mus musculus):22260 Nr1h2
Monarch:22260 Nr1h2
NCBI Gene:22260 Nr1h2
UCSC:Q60644 Nr1h2
Reference Transcript
RefSeq:NM_009473.3 Nr1h2
RefSeq:NM_001285518.1 Nr1h2
RefSeq:XM_006540804.3 Nr1h2
RefSeq:NM_001285519.1 Nr1h2
RefSeq:NM_001285517.1 Nr1h2
Other Identifiers
101981_at
10562847
1416353_at
17490312
17550412
17550414
22260
4405542
4450182
4826338
4913727
5010026
5312762
5451082
5569149
A_51_P400203
A_55_P1978481
A_66_P112009
GE33869
GO:0000122
GO:0000978
GO:0000981
GO:0001228
GO:0003677
GO:0003700
GO:0004879
GO:0005515
GO:0005634
GO:0005737
GO:0006351
GO:0006355
GO:0006357
GO:0006629
GO:0008270
GO:0009755
GO:0010628
GO:0010629
GO:0010867
GO:0010875
GO:0010884
GO:0010887
GO:0016071
GO:0016192
GO:0022600
GO:0023052
GO:0030154
GO:0031490
GO:0032369
GO:0032376
GO:0034191
GO:0036151
GO:0042632
GO:0042789
GO:0043226
GO:0043565
GO:0044255
GO:0045723
GO:0045861
GO:0045892
GO:0045893
GO:0045944
GO:0046872
GO:0046965
GO:0048384
GO:0048550
GO:0051117
GO:0051247
GO:0055088
GO:0060089
GO:0065003
GO:0090108
GO:0090187
GO:0090340
GO:0090575
GO:0120163
GO:0140110
GO:1902895
GO:1903573
ILMN_2541035
ILMN_3014084
ILMN_3085126
Msa.33515.0_s_at
U09419_s_at
Participates
as a component of
NR1H2:hydroxycholesterol [nucleoplasm] (Mus musculus)
NR1H2:RXRA [nucleoplasm] (Mus musculus)
as a member of
NR1H2,NR1H3 [nucleoplasm] (Mus musculus)
NR [nucleoplasm] (Mus musculus)
Other forms of this molecule
Nr1h2 [cytosol]
Nr1h2 [nucleoplasm]
Inferred From
NR1H2 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001272447.1
,
XP_006540867.1
,
NP_033499.1
,
NP_001272448.1
,
NP_001272446.1
Ensembl
ENSMUSP00000103545
,
ENSMUSP00000126788
,
ENSMUSP00000073188
,
ENSMUSG00000060601
,
ENSMUST00000107912
,
ENSMUST00000167197
,
ENSMUST00000073488
PRO
Q60644
MGI
1352463
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96EB6 SIRT1
1
SIRT1 [nucleoplasm]
(R-HSA-427531)
0.499
2
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