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Pdgfa [extracellular region]
Stable Identifier
R-MMU-380739
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
extracellular region
Synonyms
PDGFA-2, P20033
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
Negative regulation of the PI3K/AKT network (Mus musculus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
Activator:PI3K [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
Activator:PI3K [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
RAS GEFs promote RAS nucleotide exchange (Mus musculus)
RAS GEFs [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by PDGF (Mus musculus)
Autophosphorylation of PDGF alpha receptors (Mus musculus)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Mus musculus)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Autophosphorylation of PDGF alpha/beta receptors (Mus musculus)
PDGF alpha/beta:PDGF AB and BB dimers [plasma membrane] (Mus musculus)
PDGF AB or BB homodimers [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Phospho PDGF alpha-beta dimer:PDGF AB or BB dimers [plasma membrane] (Mus musculus)
PDGF AB or BB homodimers [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Downstream signal transduction (Mus musculus)
Activated PLC gamma dissociates from the PDGF receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Activation of Src (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Crk binds to the active PDGF receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
GRB2:SOS1 complex binds to the active receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Grb7 binds to the active PDGF receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Nck binds to the active PDGF receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PI3-kinase binds to the active receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PLC-gamma binds to the active receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
Phosphorylation of PLCgamma by PDGFR (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
SH2 domain of Src binds to the active receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
SHP2 binds to the active receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
STAT binds to the active receptor (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
p130Cas and C3G bind PDGFR bound Crk (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF dimer binds two receptors simultaneously (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF:PDGF receptor dimer [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGF-AB clevage by Furin (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGFRs bind type I TKI (Mus musculus)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Mus musculus)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Mus musculus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
PTPN12 dephosphorylates PDGFRB at Y1021 (Mus musculus)
p-PDGFRB homo and heterodimers [plasma membrane] (Mus musculus)
Phospho PDGF alpha-beta dimer:PDGF AB or BB dimers [plasma membrane] (Mus musculus)
PDGF AB or BB homodimers [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
p-PDGFRB homo and heterodimers dephosphorylated at Y1021 [plasma membrane] (Mus musculus)
Phospho PDGF alpha-beta dimer:PDGF AB or BB dimers dephosphorylated at Y1021 of PDGFRB [plasma membrane] (Mus musculus)
PDGF AB or BB homodimers [extracellular region] (Mus musculus)
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Pdgfa [extracellular region] (Mus musculus)
External Reference Information
External Reference
UniProt:P20033
Gene Names
Pdgfa
Reference Genes
BioGPS Gene:18590 Pdgfa
ENSEMBL:ENSMUSG00000025856
ENSEMBL:ENSMUSG00000025856.16 Pdgfa
KEGG Gene (Mus musculus):18590 Pdgfa
Monarch:18590 Pdgfa
NCBI Gene:18590 Pdgfa
Reference Transcript
RefSeq:XM_011240971.2 Pdgfa
RefSeq:XM_006504659.3 Pdgfa
RefSeq:NM_008808.3 Pdgfa
Participates
as a component of
PDGF A/B heterodimer [extracellular region] (Mus musculus)
Other forms of this molecule
Pdgfa [platelet alpha granule lumen]
Pdgfa [endoplasmic reticulum lumen]
Pdgfa [endoplasmic reticulum lumen]
Pdgfa [Golgi lumen]
Pdgfa [Golgi membrane]
Pdgfa [Golgi membrane]
Pdgfa [extracellular region]
Inferred From
PDGFA-2 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
XP_006504722.1
,
NP_032834.1
,
XP_011239273.1
PRO
P20033
MGI
97527
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