Reactome | EIF2AK3 [endoplasmic reticulum membrane]

EIF2AK3 [endoplasmic reticulum membrane]

Stable Identifier

R-MMU-381046

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

endoplasmic reticulum membrane

Synonyms

Q9Z2B5

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Z2B5 Eif2ak3

Gene Names

Eif2ak3, Pek, Perk

Chain

signal peptide:1-28, chain:29-1114

Reference Genes

BioGPS Gene:13666 Eif2ak3

KEGG Gene (Mus musculus):13666 Eif2ak3

Monarch:13666 Eif2ak3

NCBI Gene:13666 Eif2ak3

UCSC:Q9Z2B5 Eif2ak3

Reference Transcript

RefSeq:NM_001313918.1 Eif2ak3

Participates

as an input of

Dimerization of PERK (Mus musculus)

as a component of

Other forms of this molecule

Eif2ak3 [endoplasmic reticulum membrane]

Inferred From

EIF2AK3 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001300847.1

IntEnz

2.7.11.1

PRO

Q9Z2B5

MGI

1341830

PDB

3QD2, 4YZY

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27958-PRO_0000037570			0.656	5
UniProt:P05198 EIF2S1	2	p-S52-EIF2S1 [cytosol] (R-HSA-381060) EIF2S1 [cytosol] (R-HSA-72510)	0.655	4
UniProt:Q9QXT0 CNPY2			0.611	7
UniProt:Q9Z2B5 Eif2ak3	2	Eif2ak3 [endoplasmic reticulum membrane] (R-MMU-9842185) EIF2AK3 [endoplasmic reticulum membrane] (R-MMU-381046)	0.558	2
UniProt:Q80U63	2	MFN2 [mitochondrial outer membrane] (R-MMU-992714) K48polyUb-MFN2 [mitochondrial outer membrane] (R-MMU-5205668)	0.524	2

Cite Us!