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CRK, CRKL [cytosol]
Stable Identifier
R-MMU-381945
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Mus musculus)
Regulation of signaling by CBL (Mus musculus)
CBL binds CRK (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
p(Y700,731,774)-CBL:CRK [cytosol] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
CBL:CRKL binds RAPGEF1 (Mus musculus)
p(Y700,731,774)-CBL:CRK [cytosol] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Mus musculus)
p(Y700,731,774)-CBL:CRK [cytosol] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by MET (Mus musculus)
MET promotes cell motility (Mus musculus)
MET activates RAP1 and RAC1 (Mus musculus)
CRK,CRKL recruits RAC1 GEF to activated MET (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
DOCK7 activates RAC1 (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
GAB1 recruits CRK,CRKL to MET (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
RAPGEF1 activates RAP1 (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
RAPGEF1 binds CRK,CRKL (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
MET receptor recycling (Mus musculus)
GGA3 associates with activated MET receptor (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
Signaling by PDGF (Mus musculus)
Downstream signal transduction (Mus musculus)
Crk binds to the active PDGF receptor (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
p130Cas and C3G bind PDGFR bound Crk (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Mus musculus)
CRK, CRKL [cytosol] (Mus musculus)
Participants
members
Crkl [cytosol]
(Mus musculus)
Crk [cytosol]
(Mus musculus)
Participates
as an input of
Crk binds to the active PDGF receptor (Mus musculus)
CBL binds CRK (Mus musculus)
GAB1 recruits CRK,CRKL to MET (Mus musculus)
as a component of
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Mus musculus)
p(Y700,731,774)-CBL:CRK [cytosol] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
Inferred From
CRK, CRKL [cytosol]
(Homo sapiens)
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