Reactome | Ntsr2 [plasma membrane]

Ntsr2 [plasma membrane]

Stable Identifier

R-MMU-388918

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

NTSR2, P70310

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2 [plasma membrane] (Mus musculus)
        
        Ntsr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2 [plasma membrane] (Mus musculus)
        
        Ntsr2 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2 [plasma membrane] (Mus musculus)
        
        Ntsr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2 [plasma membrane] (Mus musculus)
        
        Ntsr2 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2 [plasma membrane] (Mus musculus)
        
        Ntsr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2 [plasma membrane] (Mus musculus)
        
        Ntsr2 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Neurotensin receptors can bind neurotensins (Mus musculus)
        
        NTSR1,NTSR2 [plasma membrane] (Mus musculus)
        
        Ntsr2 [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Mus musculus)
        
        NTSR1,NTSR2 [plasma membrane] (Mus musculus)
        
        Ntsr2 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P70310

Gene Names

Ntsr2

Reference Genes

BioGPS Gene:18217 Ntsr2

ENSEMBL:ENSMUSG00000020591

ENSEMBL:ENSMUSG00000020591.12 Ntsr2

KEGG Gene (Mus musculus):18217 Ntsr2

Monarch:18217 Ntsr2

NCBI Gene:18217 Ntsr2

UCSC:P70310 Ntsr2

Reference Transcript

RefSeq:NM_008747.2 Ntsr2

Other Identifiers

10394685

1417151_a_at

17274195

18217

4392003

4481567

4651540

4703675

4898486

4945396

5059872

5062378

5207186

93137_at

A_52_P266686

A_55_P1974527

GO:0004930

GO:0005794

GO:0005802

GO:0005886

GO:0007165

GO:0007186

GO:0007200

GO:0007218

GO:0009986

GO:0016020

GO:0016492

GO:0023052

GO:0042391

GO:0042802

GO:0043198

GO:0043204

GO:0043226

GO:0043410

GO:0044877

GO:0060089

GO:0070374

ILMN_2769234

U51908_s_at

mMC002571

Participates

as a member of

NTSR1,NTSR2 [plasma membrane] (Mus musculus)

Inferred From

NTSR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032773.2

Ensembl

ENSMUSG00000020591, ENSMUSP00000106693, ENSMUST00000111064

PRO

P70310

MGI

108018