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CDC42:GTP, RAC1:GTP [plasma membrane]
Stable Identifier
R-MMU-389778
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
Active RAC1/CDC42
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Costimulation by the CD28 family (Mus musculus)
CD28 co-stimulation (Mus musculus)
CD28 dependent Vav1 pathway (Mus musculus)
Activation of PAKs by RAC1 and CDC42 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
Innate Immune System (Mus musculus)
Fcgamma receptor (FCGR) dependent phagocytosis (Mus musculus)
Regulation of actin dynamics for phagocytic cup formation (Mus musculus)
Autophosphorylation of PAK1 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1 and CDC42 activate PAK1 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK6/MAPK4 signaling (Mus musculus)
Activation of PAKs by RAC1 and CDC42 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
Autophosphorylation of PAK1,2,3 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases activate IQGAPs (Mus musculus)
GTP-bound RAC1 and CDC42 bind IQGAPs (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Mus musculus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
IQGAP1 binds CLIP1 and microtubules (Mus musculus)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
IQGAPs bind CALM1 (Mus musculus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
IQGAPs bind F-actin, which is inhibited by calmodulin (Mus musculus)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RHO GTPases activate PAKs (Mus musculus)
Autophosphorylation of PAK1,2,3 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1 and CDC42 activate PAK1 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1 and CDC42 activate PAK2 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1 and CDC42 activate PAK3 (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Mus musculus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
Participants
members
Cdc42:GTP [plasma membrane]
(Mus musculus)
Rac1-GTP [cytosol]
(Mus musculus)
Participates
as an input of
Activation of PAKs by RAC1 and CDC42 (Mus musculus)
GTP-bound RAC1 and CDC42 bind IQGAPs (Mus musculus)
RAC1 and CDC42 activate PAK3 (Mus musculus)
RAC1 and CDC42 activate PAK1 (Mus musculus)
RAC1 and CDC42 activate PAK2 (Mus musculus)
as a component of
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Mus musculus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Mus musculus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Mus musculus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Mus musculus)
as an output of
Autophosphorylation of PAK1,2,3 (Mus musculus)
Autophosphorylation of PAK1 (Mus musculus)
Inferred From
CDC42:GTP, RAC1:GTP [plasma membrane]
(Homo sapiens)
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