Reactome | Chrm1 [plasma membrane]

Chrm1 [plasma membrane]

Stable Identifier

R-MMU-390628

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

CHRM1, P12657

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Amine ligand-binding receptors (Mus musculus)
        
        Muscarinic acetylcholine receptors (Mus musculus)
        
        CHRM1,3,5 bind CHRM1,3,5 antagonists (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:CHRM1,3,5 antagonists [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 bind acetylcholine (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P12657

Gene Names

Chrm1

Reference Genes

BioGPS Gene:12669 Chrm1

ENSEMBL:ENSMUSG00000032773

KEGG:mmu:12669 Chrm1

Monarch:12669 Chrm1

NCBI Gene:12669 Chrm1

UCSC:P12657 Chrm1

Reference Transcript

Other Identifiers

101829_at

10461143

12669

1439611_at

1450833_at

17357120

4311736

4424635

4497342

4529037

4685308

4873245

4880685

4964887

5027894

5028289

5140232

5203554

5291283

5426899

5460861

A_52_P393577

A_52_P85372

A_55_P2055262

GE1391137

GE34853

GO:0004930

GO:0004993

GO:0005886

GO:0007186

GO:0007187

GO:0007197

GO:0007213

GO:0007268

GO:0007274

GO:0016020

GO:0016907

GO:0022600

GO:0023052

GO:0030425

GO:0032279

GO:0040012

GO:0042734

GO:0043270

GO:0043679

GO:0045202

GO:0045211

GO:0046541

GO:0050877

GO:0050890

GO:0060078

GO:0060089

GO:0090316

GO:0098664

GO:0098685

GO:0098839

GO:0098978

GO:0098981

GO:0099170

ILMN_1238387

ILMN_2509775

ILMN_2889376

Msa.399.0_at

mMC018620

Participates

as a member of

CHRM1,3,5 [plasma membrane] (Mus musculus)

Inferred From

CHRM1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001106167.1, NP_031724.2

ZINC - World Drugs

ACM1_MOUSE

ENSEMBL

ENSMUSP00000042632, ENSMUSP00000126103, ENSMUST00000163785, ENSMUST00000035444

ZINC - FDA approved

ACM1_MOUSE

ZINC - Substances

ACM1_MOUSE

ZINC - Biogenic

ACM1_MOUSE

ZINC target

P12657

PRO

P12657

GlyGen

P12657

MGI

88396

ZINC - Investigational

ACM1_MOUSE

ZINC - Metabolites

ACM1_MOUSE

ZINC - Predictions - Purchasable

ACM1_MOUSE