Reactome | Chrm3 [plasma membrane]

Chrm3 [plasma membrane]

Stable Identifier

R-MMU-399994

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

CHRM3, Q9ERZ3

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Amine ligand-binding receptors (Mus musculus)
        
        Muscarinic acetylcholine receptors (Mus musculus)
        
        CHRM1,3,5 bind CHRM1,3,5 antagonists (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:CHRM1,3,5 antagonists [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 bind acetylcholine (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm3 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9ERZ3 Chrm3

Gene Names

Chrm3, Chrm-3

Chain

chain:1-589

Reference Genes

BioGPS Gene:12671 Chrm3

KEGG:mmu:12671 Chrm3

Monarch:12671 Chrm3

NCBI Gene:12671 Chrm3

UCSC:Q9ERZ3 Chrm3

Reference Transcript

Other Identifiers

10407591

12671

1422258_at

17290447

4398463

4631597

4717370

4752738

5136171

5347976

5364228

5389026

5493622

A_51_P247853

A_52_P92072

A_55_P1955681

GE41848

GO:0003012

GO:0003013

GO:0003056

GO:0003063

GO:0004930

GO:0004993

GO:0005515

GO:0005783

GO:0005789

GO:0005886

GO:0006939

GO:0006940

GO:0007186

GO:0007187

GO:0007197

GO:0007207

GO:0007213

GO:0007268

GO:0007271

GO:0009925

GO:0016020

GO:0016323

GO:0016328

GO:0016907

GO:0019722

GO:0022600

GO:0023052

GO:0030054

GO:0030425

GO:0031789

GO:0032024

GO:0032279

GO:0042166

GO:0042734

GO:0043226

GO:0043679

GO:0045202

GO:0045211

GO:0045907

GO:0045987

GO:0046541

GO:0050997

GO:0060089

GO:0095500

GO:0098664

GO:0098839

GO:0098978

GO:0099105

GO:1904695

GO:1905144

GO:1990806

ILMN_1235355

ILMN_2655907

mMC011603

Participates

as a member of

CHRM1,3,5 [plasma membrane] (Mus musculus)

Other forms of this molecule

Muscarinic acetylcholine receptor M3 [plasma membrane]

Inferred From

CHRM3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_006516531.1, NP_150372.1

ZINC - Investigational

ACM3_MOUSE

ZINC - World Drugs

ACM3_MOUSE

ENSEMBL

ENSMUSP00000055579, ENSMUSP00000140131, ENSMUST00000187510, ENSMUST00000063093

ZINC - FDA approved

ACM3_MOUSE

ZINC - Substances

ACM3_MOUSE

ZINC target

Q9ERZ3

PRO

Q9ERZ3

GlyGen

Q9ERZ3

MGI

88398

ZINC - Predictions - Purchasable

ACM3_MOUSE