Reactome | Esr1 [nucleoplasm]

Esr1 [nucleoplasm]

Stable Identifier

R-MMU-4090302

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

monoSUMO1-5K-ESR1, P19785

Locations in the PathwayBrowser for interactor UniProt:O94763 RMP

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External Reference Information

External Reference

UniProt:P19785

Gene Names

Esr1

Reference Genes

BioGPS Gene:13982 Esr1

ENSEMBL:ENSMUSG00000019768

ENSEMBL:ENSMUSG00000019768 Esr1

KEGG Gene (Mus musculus):13982 Esr1

Monarch:13982 Esr1

NCBI Gene:13982 Esr1

UCSC:P19785 Esr1

Reference Transcript

Other Identifiers

10367600

115428_at

133838_at

13982

1421244_at

1435663_at

1460591_at

17231461

4317834

4353759

4384824

4420592

4479263

4483165

4616323

4619918

4654764

4733540

4814266

4916124

4921789

5053712

5054212

5121005

5343839

5395079

5450558

5486154

93945_at

93946_at

93947_g_at

A_51_P474658

A_52_P237077

A_55_P2030883

GE42492

GO:0000122

GO:0000278

GO:0000785

GO:0000791

GO:0000978

GO:0001093

GO:0001221

GO:0001222

GO:0001223

GO:0001228

GO:0001547

GO:0002064

GO:0002376

GO:0003676

GO:0003677

GO:0003682

GO:0003700

GO:0003707

GO:0004879

GO:0005496

GO:0005515

GO:0005622

GO:0005634

GO:0005667

GO:0005694

GO:0005737

GO:0005739

GO:0005794

GO:0005886

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0006629

GO:0006954

GO:0007200

GO:0007204

GO:0008013

GO:0008134

GO:0008209

GO:0008270

GO:0008289

GO:0008584

GO:0010629

GO:0010863

GO:0012501

GO:0016020

GO:0017025

GO:0019899

GO:0019901

GO:0022414

GO:0023052

GO:0030154

GO:0030284

GO:0030315

GO:0030331

GO:0030518

GO:0030520

GO:0031047

GO:0031798

GO:0032355

GO:0032991

GO:0034056

GO:0034121

GO:0036312

GO:0042562

GO:0042802

GO:0043005

GO:0043124

GO:0043195

GO:0043204

GO:0043226

GO:0043401

GO:0043433

GO:0043523

GO:0043565

GO:0043627

GO:0044877

GO:0045429

GO:0045742

GO:0045839

GO:0045893

GO:0045899

GO:0045944

GO:0046325

GO:0046872

GO:0048144

GO:0048146

GO:0048471

GO:0048662

GO:0048856

GO:0048863

GO:0050679

GO:0050727

GO:0051000

GO:0051091

GO:0051117

GO:0055065

GO:0055085

GO:0060011

GO:0060065

GO:0060068

GO:0060089

GO:0060523

GO:0060527

GO:0060687

GO:0060745

GO:0060749

GO:0060750

GO:0065003

GO:0070374

GO:0071168

GO:0071391

GO:0071392

GO:0090209

GO:0097550

GO:0140014

GO:1901215

GO:1903799

GO:1904035

GO:1990837

GO:1990841

ILMN_2604666

ILMN_2726412

Msa.625.0_at

mMC011627

mMR027653

Participates

as an output of

PIAS1,3 SUMOylate ESR1 with SUMO1 (Mus musculus)

Other forms of this molecule

phospho-Esr1 [nucleoplasm]

Esr1 [plasma membrane]

Esr1 [cytosol]

Esr1 [nucleoplasm]

Esr1 [cytosol]

Inferred From

monoSUMO1-5K-ESR1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 266 (in Homo sapiens)

Coordinate

266

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 268 (in Homo sapiens)

Coordinate

268

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 299 (in Homo sapiens)

Coordinate

299

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 302 (in Homo sapiens)

Coordinate

302

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 303 (in Homo sapiens)

Coordinate

303

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

XP_006512498.1, XP_011241369.1, XP_006512497.1, XP_011241370.1, XP_006512496.1, XP_011241368.1, NP_031982.1, NP_001289460.1, NP_001289461.1

ZINC - Metabolites

ESR1_MOUSE

ZINC - World Drugs

ESR1_MOUSE

ZINC - FDA approved

ESR1_MOUSE

ZINC - Substances

ESR1_MOUSE

ZINC - Biogenic

ESR1_MOUSE

ZINC target

P19785

Ensembl

ENSMUSP00000101214, ENSMUST00000105590, ENSMUST00000105589, ENSMUST00000067086, ENSMUSP00000101215, ENSMUSG00000019768, ENSMUSP00000070070

PRO

P19785

MGI

1352467

ZINC - Predictions - Purchasable

ESR1_MOUSE

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15788 NCOA1	3	monoSUMO1-K732,K774-NCOA1 [nucleoplasm] (R-HSA-4085291) NCOA1 (868-1441) [nucleoplasm] (R-HSA-5603230) NCOA1 [nucleoplasm] (R-HSA-442496)	0.646	3
UniProt:O94763 RMP			0.499	2
UniProt:Q00175	3	Pgr [nucleoplasm] (R-MMU-4341032) Pgr [cytosol] (R-MMU-8948964) Pgr [nucleoplasm] (R-MMU-3008952)	0.463	5

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