Reactome | monoSUMO1-5K-ESR1 [nucleoplasm]

monoSUMO1-5K-ESR1 [nucleoplasm]

Stable Identifier

R-MMU-4090302

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

P19785

Locations in the PathwayBrowser for interactor UniProt:O94763 RMP

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External Reference Information

External Reference

UniProt:P19785

Reference Genes

BioGPS Gene:13982

ENSEMBL:ENSMUSG00000019768

KEGG:mmu:13982

Monarch:13982

NCBI Gene:13982

UCSC:P19785

Reference Transcript

Other Identifiers

10367600

115428_at

133838_at

13982

1421244_at

1435663_at

1460591_at

161113_at

17231461

4313312

4317834

4345861

4353759

4381939

4384824

4391841

4420592

4479263

4483165

4560020

4616323

4619918

4654764

4678469

4733540

4743102

4814266

4847274

4916124

4921789

5019796

5036182

5053712

5054212

5115152

5121005

5147081

5225794

5261698

5266658

5343839

5395079

5450558

5486154

5521289

5536375

5573142

93945_at

93946_at

93947_g_at

A_51_P474658

A_52_P237077

A_55_P2030883

A_55_P2716924

A_55_P2899365

A_65_P17231

A_66_P138072

GE42492

GO:0000122

GO:0000785

GO:0000791

GO:0000978

GO:0001093

GO:0001221

GO:0001222

GO:0001223

GO:0001228

GO:0001547

GO:0002064

GO:0003677

GO:0003682

GO:0003700

GO:0003707

GO:0004879

GO:0005496

GO:0005515

GO:0005634

GO:0005667

GO:0005737

GO:0005794

GO:0005886

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0006629

GO:0007200

GO:0007204

GO:0008013

GO:0008134

GO:0008209

GO:0008270

GO:0008289

GO:0008584

GO:0010629

GO:0017025

GO:0019899

GO:0019901

GO:0022414

GO:0030154

GO:0030284

GO:0030315

GO:0030331

GO:0030518

GO:0030520

GO:0031798

GO:0032355

GO:0032991

GO:0034056

GO:0034121

GO:0034392

GO:0036312

GO:0042562

GO:0042802

GO:0043124

GO:0043195

GO:0043204

GO:0043226

GO:0043401

GO:0043433

GO:0043524

GO:0043565

GO:0043627

GO:0044877

GO:0045429

GO:0045742

GO:0045839

GO:0045893

GO:0045944

GO:0046325

GO:0046872

GO:0048144

GO:0048146

GO:0048471

GO:0048662

GO:0048856

GO:0048863

GO:0050679

GO:0050727

GO:0051000

GO:0051091

GO:0051117

GO:0051123

GO:0060011

GO:0060065

GO:0060068

GO:0060089

GO:0060523

GO:0060527

GO:0060687

GO:0060745

GO:0060749

GO:0060750

GO:0065003

GO:0070374

GO:0071168

GO:0071391

GO:0071392

GO:0071889

GO:0090209

GO:0140110

GO:1902894

GO:1904035

GO:1990837

GO:1990841

ILMN_1221362

ILMN_2571180

ILMN_2604666

ILMN_2726412

Msa.625.0_at

mMC011627

mMR027653

Participates

as an output of

PIAS1,3 SUMOylate ESR1 with SUMO1 (Mus musculus)

Other forms of this molecule

ESR1 [cytosol]

ESR1 [nucleoplasm]

Me87-PalmS-ER alpha36 [plasma membrane]

Me260-PalmS-ESR1 [plasma membrane]

PalmS-ER alpha36 [plasma membrane]

PalmS-ESR1 [plasma membrane]

PalmS-ER alpha46 [cytosol]

PalmS-ESR1 [cytosol]

Me260-ESR1 [cytosol]

phospho-p-S167-ESR1 [cytosol]

phospho-p-S167-ESR1 [nucleoplasm]

phospho-p-S118-ESR1 [nucleoplasm]

Inferred From

monoSUMO1-5K-ESR1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 266 (in Homo sapiens)

Coordinate

266

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 268 (in Homo sapiens)

Coordinate

268

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 299 (in Homo sapiens)

Coordinate

299

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 302 (in Homo sapiens)

Coordinate

302

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 303 (in Homo sapiens)

Coordinate

303

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

XP_006512496.1, XP_006512497.1, XP_006512498.1, XP_011241368.1, XP_011241369.1, XP_011241370.1, NP_031982.1, NP_001289461.1, NP_001289460.1

ZINC - Metabolites

ESR1_MOUSE

ENSEMBL

ENSMUSP00000101214, ENSMUSP00000101215, ENSMUST00000105590, ENSMUST00000105589, ENSMUST00000067086, ENSMUSP00000070070, ENSMUSG00000019768

ZINC - FDA approved

ESR1_MOUSE

ZINC - Substances

ESR1_MOUSE

ZINC - Biogenic

ESR1_MOUSE

ZINC target

P19785

PRO

P19785

MGI

1352467

GlyGen

P19785

ZINC - Predictions - Purchasable

ESR1_MOUSE

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15788 NCOA1	3	NCOA1 [nucleoplasm] (R-HSA-442496) NCOA1 (868-1441) [nucleoplasm] (R-HSA-5603230) monoSUMO1-K732,K774-NCOA1 [nucleoplasm] (R-HSA-4085291)	0.646	3
UniProt:O94763 RMP			0.499	2
UniProt:Q00175	3	monoSUMO1-K7,K388,K531-PGR [nucleoplasm] (R-MMU-4341032) PGR [cytosol] (R-MMU-8948964) PGR [nucleoplasm] (R-MMU-3008952)	0.463	5

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