Reactome | Adora1 [plasma membrane]

Adora1 [plasma membrane]

Stable Identifier

R-MMU-418941

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

ADORA1, Q60612

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora1 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora1 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora1 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Nucleotide-like (purinergic) receptors (Mus musculus)
        
        Adenosine P1 receptors (Mus musculus)
        
        A1 and A3 receptors bind adenosine (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora1 [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q60612

Gene Names

Adora1

Reference Genes

BioGPS Gene:11539 Adora1

ENSEMBL:ENSMUSG00000042429

ENSEMBL:ENSMUSG00000042429.10 Adora1

KEGG Gene (Mus musculus):11539 Adora1

Monarch:11539 Adora1

NCBI Gene:11539 Adora1

UCSC:Q60612 Adora1

Reference Transcript

Other Identifiers

10357878

11539

1427331_at

1435495_at

163668_at

17227094

4330384

4400020

4585595

4802749

4832646

5174154

5248556

5459941

5479620

5545330

92374_at

A_52_P172272

A_52_P661412

A_55_P2101776

A_66_P140422

GE1401754

GO:0001609

GO:0001659

GO:0001664

GO:0001666

GO:0001883

GO:0001973

GO:0002087

GO:0002376

GO:0002674

GO:0002686

GO:0002793

GO:0003012

GO:0003013

GO:0003014

GO:0003016

GO:0003084

GO:0003085

GO:0003093

GO:0004930

GO:0005515

GO:0005886

GO:0006612

GO:0006629

GO:0006886

GO:0006954

GO:0007165

GO:0007186

GO:0007193

GO:0008285

GO:0010035

GO:0010646

GO:0012501

GO:0014050

GO:0014074

GO:0016020

GO:0016042

GO:0016323

GO:0023051

GO:0023052

GO:0030425

GO:0030673

GO:0031072

GO:0031683

GO:0032229

GO:0032244

GO:0032279

GO:0032795

GO:0032900

GO:0035307

GO:0036211

GO:0042311

GO:0042321

GO:0042323

GO:0042734

GO:0043025

GO:0043066

GO:0043195

GO:0043197

GO:0043268

GO:0043410

GO:0044297

GO:0044305

GO:0044877

GO:0045202

GO:0045211

GO:0045776

GO:0045777

GO:0046888

GO:0046982

GO:0048786

GO:0048870

GO:0050728

GO:0050877

GO:0050890

GO:0050896

GO:0050900

GO:0050965

GO:0050995

GO:0050996

GO:0051930

GO:0051967

GO:0055065

GO:0055089

GO:0055117

GO:0060079

GO:0060089

GO:0060292

GO:0070254

GO:0070256

GO:0070328

GO:0086004

GO:0099509

GO:0110165

GO:0140928

GO:1900272

GO:1900453

ILMN_1254016

ILMN_3065420

ILMN_3143358

mMC002942

Participates

as a member of

ADORA1,3 [plasma membrane] (Mus musculus)

Inferred From

ADORA1 [plasma membrane] (Homo sapiens)

Cross References

ZINC - Investigational

AA1R_MOUSE

RefSeq

XP_006529142.1, NP_001008533.1, NP_001278857.1, NP_001034599.1, NP_001269874.1

ZINC - Substances

AA1R_MOUSE

Ensembl

ENSMUST00000038191, ENSMUSG00000042429, ENSMUSP00000043522, ENSMUSP00000083656, ENSMUST00000086465

ZINC target

Q60612

PRO

Q60612

ZINC - Predictions - Purchasable

AA1R_MOUSE

MGI

99401

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