Reactome | Pspn [extracellular region]

Pspn [extracellular region]

Stable Identifier

R-MMU-434907

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

PSPN, O70300

Locations in the PathwayBrowser

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Developmental Biology (Mus musculus)

- Nervous system development (Mus musculus)
  - Axon guidance (Mus musculus)
    - RET signaling (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - PKA phosphorylates RET:GDNF:GFRA dimer (Mus musculus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - PSPN binds RET:GFRA4 (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - RET dimerizes (Mus musculus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - RET tyrosine phosphorylation (Mus musculus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - SHC1 in the RET complex is phosphorylated (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - p-5Y-RET complexes bind GRB2 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
      - p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)

Signal Transduction (Mus musculus)

- MAPK family signaling cascades (Mus musculus)
  - MAPK1/MAPK3 signaling (Mus musculus)
    - RAF/MAP kinase cascade (Mus musculus)
      - RAS GEFs promote RAS nucleotide exchange (Mus musculus)
        
        RAS GEFs [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Mus musculus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Mus musculus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Mus musculus)
        
        Pspn [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:O70300

Gene Names

Pspn

Reference Genes

ENSEMBL:ENSMUSG00000002664

Participates

as an input of

PSPN binds RET:GFRA4 (Mus musculus)

as a component of

Inferred From

PSPN [extracellular region] (Homo sapiens)

Cross References

PRO

O70300

MGI

1201684

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