Reactome | Prok1 [extracellular region]

Prok1 [extracellular region]

Stable Identifier

R-MMU-444616

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

PROK1, Q14A28

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok1 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok1 [extracellular region] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok1 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok1 [extracellular region] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok1 [extracellular region] (Mus musculus)
        
        Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok1 [extracellular region] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Prokineticin receptors bind prokineticin (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok1 [extracellular region] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok1 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:Q14A28

Gene Names

Prok1

Reference Genes

BioGPS Gene:246691 Prok1

ENSEMBL:ENSMUSG00000070368

KEGG:mmu:246691 Prok1

Monarch:246691 Prok1

NCBI Gene:246691 Prok1

UCSC:Q14A28 Prok1

Reference Transcript

Other Identifiers

10501084

131855_at

1443505_at

17408985

246691

4438997

4547688

4558238

4607388

4608247

4709530

5143936

5209356

5264813

A_52_P306357

A_52_P482724

A_55_P2163183

GE1529561

GO:0001525

GO:0001664

GO:0001935

GO:0005576

GO:0007165

GO:0007623

GO:0008083

GO:0008283

GO:0043410

GO:0045765

GO:0048018

GO:0051781

GO:0098772

GO:0101023

GO:1905564

ILMN_1233213

ILMN_2886025

mMC022230

Participates

as a member of

PROK1,PROK2 [extracellular region] (Mus musculus)

Inferred From

PROK1 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_017175073.1, NP_001037847.1

ENSEMBL

ENSMUST00000049852, ENSMUSP00000143197, ENSMUST00000197758, ENSMUSP00000060617

PRO

Q14A28

MGI

2180370