Reactome | Prok2 [extracellular region]

Prok2 [extracellular region]

Stable Identifier

R-MMU-444660

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

PROK2, Q9QXU7

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok2 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok2 [extracellular region] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok2 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok2 [extracellular region] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok2 [extracellular region] (Mus musculus)
        
        Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok2 [extracellular region] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Prokineticin receptors bind prokineticin (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok2 [extracellular region] (Mus musculus)
        
        PROKR1,PROKR2:PROK1,PROK2 [plasma membrane] (Mus musculus)
        
        PROK1,PROK2 [extracellular region] (Mus musculus)
        
        Prok2 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9QXU7

Gene Names

Prok2

Reference Genes

BioGPS Gene:50501 Prok2

ENSEMBL:ENSMUSG00000030069

KEGG:mmu:50501 Prok2

Monarch:50501 Prok2

NCBI Gene:50501 Prok2

UCSC:Q9QXU7 Prok2

Reference Transcript

Other Identifiers

10546695

1419681_a_at

1426176_a_at

1451952_at

17469455

4437812

4558716

4648774

4831658

50501

5180104

5259288

5324714

A_51_P429252

A_52_P158476

A_55_P2741258

GE36874

GO:0001525

GO:0001664

GO:0001935

GO:0003349

GO:0005576

GO:0006935

GO:0007218

GO:0007283

GO:0007623

GO:0022414

GO:0030154

GO:0043066

GO:0045987

GO:0048511

GO:0048856

GO:0060976

GO:0060979

GO:0060983

ILMN_2653528

ILMN_3147259

mMC008662

Participates

as a member of

PROK1,PROK2 [extracellular region] (Mus musculus)

Inferred From

PROK2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_056583.1, NP_001032628.1

ENSEMBL

ENSMUST00000101120, ENSMUSP00000144760, ENSMUST00000032152, ENSMUST00000203738, ENSMUSP00000032152, ENSMUSP00000098678

PRO

Q9QXU7

MGI

1354178