Reactome | Il33 [extracellular region]

Il33 [extracellular region]

Stable Identifier

R-MMU-448567

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

IL33, Q8BVZ5

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - Negative regulation of the PI3K/AKT network (Mus musculus)
      - PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Mus musculus)
        
        PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer [plasma membrane] (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1 [plasma membrane] (Mus musculus)
        
        IL1RL1:IL33 [plasma membrane] (Mus musculus)
        
        Il33 [extracellular region] (Mus musculus)
    - PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
      - IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer [plasma membrane] (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1 [plasma membrane] (Mus musculus)
        
        IL1RL1:IL33 [plasma membrane] (Mus musculus)
        
        Il33 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8BVZ5

Gene Names

Il33

Reference Genes

BioGPS Gene:77125 Il33

ENSEMBL:ENSMUSG00000024810

ENSEMBL:ENSMUSG00000024810.17 Il33

KEGG Gene (Mus musculus):77125 Il33

Monarch:77125 Il33

NCBI Gene:77125 Il33

UCSC:Q8BVZ5 Il33

Reference Transcript

Other Identifiers

10462442

113122_i_at

113123_r_at

1416200_at

17358598

4816321

4927655

4970606

5017403

5142290

5212337

5245313

5342564

5402396

5451577

5564388

77125

A_51_P122321

A_55_P1964960

A_55_P2614900

GE127221

GO:0000122

GO:0001819

GO:0002112

GO:0002281

GO:0002282

GO:0002376

GO:0002638

GO:0002639

GO:0002686

GO:0002826

GO:0002830

GO:0005125

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006351

GO:0006355

GO:0006606

GO:0006886

GO:0006913

GO:0006954

GO:0010186

GO:0010467

GO:0010628

GO:0012501

GO:0023052

GO:0030133

GO:0030154

GO:0030163

GO:0030225

GO:0031410

GO:0032436

GO:0032689

GO:0032722

GO:0032736

GO:0032753

GO:0032754

GO:0032755

GO:0032760

GO:0038172

GO:0042092

GO:0043032

GO:0043226

GO:0043231

GO:0045345

GO:0045348

GO:0045944

GO:0048018

GO:0048714

GO:0048856

GO:0048870

GO:0050729

GO:0051607

GO:0051770

GO:0061518

GO:0071260

GO:0097191

GO:0098542

GO:0098772

GO:0106015

GO:0120042

GO:0150142

GO:0150145

GO:1901135

ILMN_1259747

mMC000828

Participates

as an input of

IL33 binds IL1RL1 (Mus musculus)

as a component of

Other forms of this molecule

Il33 [nucleoplasm]

Inferred From

IL33 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001158196.1, XP_011245701.1, XP_006527526.1, NP_598536.2

Ensembl

ENSMUSG00000024810, ENSMUSP00000025724, ENSMUST00000025724, ENSMUST00000120388, ENSMUSP00000113829

PRO

Q8BVZ5

MGI

1924375

PDB

5VI4