JLP interacts with CDO complex

Stable Identifier
R-MMU-448954
Type
Reaction [binding]
Species
Mus musculus
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
JLP interacts with CDO complex
JLP is a scaffold protein for the p38 MAPK pathway. During myogenic differentiation JLP binds the intracellular region of CDO which in turn binds p38 leading to p38 activation. The major CDO-binding region of JLP resides between amino acids 465-647.
Literature References
PubMed ID Title Journal Year
17074887 Activation of p38alpha/beta MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein Cdo

Kang, JS, Lee, CM, Takaesu, G, Bae, GU, Yi, MJ, Krauss, RS, Reddy, EP

J Cell Biol 2006
Participants
Input
Output
Orthologous Events
JLP interacts with CDO complex (Homo sapiens)
Authored
Garapati, P V  (2008-08-11)
Reviewed
Krauss, RS  (2010-02-09)
Created
Garapati, P V  (2009-11-26)
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