Interaction of ABL1 with CDO complex

Stable Identifier
R-MMU-449198
Type
Reaction [binding]
Species
Mus musculus
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Interaction of ABL1 with CDO complex
ABL binds to the cytoplasmic tail of CDO and also to the p38 MAPK scaffold protein JLP. ABL binds a proline-rich motif in CDO via its SH3 domain, and ABL is necessary for full activation of p38 MAPK, during myogenic differentiation.
Literature References
PubMed ID Title Journal Year
19470755 Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiation

Kang, JS, Zhang, W, Bae, GU, Lee, HJ, Kim, BG, Oh, JE, Lee, SJ, Krauss, RS

Mol Cell Biol 2009
Participants
Input
Output
Orthologous Events
Interaction of ABL1 with CDO complex (Homo sapiens)
Authored
Garapati, P V  (2008-08-11)
Reviewed
Krauss, RS  (2010-02-09)
Created
Garapati, P V  (2009-12-01)
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