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Hdac1 [nucleoplasm]
Stable Identifier
R-MMU-4616030
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
monoSUMO1-K444,K476-HDAC1, O09106
Locations in the PathwayBrowser for interactor UniProt:P48432 Sox2
Expand all
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
SUMOylation (Mus musculus)
SUMO E3 ligases SUMOylate target proteins (Mus musculus)
SUMOylation of chromatin organization proteins (Mus musculus)
SUMOylation of HDAC1 with SUMO1 (Mus musculus)
Hdac1 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:O09106 Hdac1
Gene Names
Hdac1
Chain
chain:1-482
Reference Genes
BioGPS Gene:433759 Hdac1
ENSEMBL:ENSMUSG00000028800.16 Hdac1
KEGG Gene (Mus musculus):433759 Hdac1
Monarch:433759 Hdac1
NCBI Gene:433759 Hdac1
UCSC:O09106 Hdac1
Reference Transcript
RefSeq:NM_008228.2 Hdac1
Other Identifiers
10447004
10516605
1448246_at
17430397
433759
4554714
4771148
4777033
4853523
4912872
4914004
4944971
4976938
5003349
5028389
5030628
5034656
5080974
5090612
5104267
5107562
5111577
5216090
5316049
5374789
5416995
5465606
5470267
5518063
5583342
5587574
96046_at
A_55_P1970775
A_65_P09914
A_66_P128384
GO:0000118
GO:0000122
GO:0000228
GO:0000785
GO:0000792
GO:0000976
GO:0000978
GO:0000979
GO:0001046
GO:0001222
GO:0002039
GO:0003677
GO:0003682
GO:0003714
GO:0003824
GO:0004407
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0006325
GO:0006338
GO:0006346
GO:0006351
GO:0006355
GO:0006357
GO:0007492
GO:0007623
GO:0008284
GO:0009913
GO:0010629
GO:0012501
GO:0016575
GO:0016581
GO:0016787
GO:0017053
GO:0019213
GO:0019899
GO:0021766
GO:0023052
GO:0030154
GO:0030182
GO:0030336
GO:0030512
GO:0032922
GO:0032991
GO:0033558
GO:0035851
GO:0036211
GO:0042475
GO:0042659
GO:0042733
GO:0042826
GO:0043025
GO:0043066
GO:0043124
GO:0043226
GO:0043922
GO:0044877
GO:0045892
GO:0045893
GO:0045944
GO:0046872
GO:0048471
GO:0048511
GO:0048709
GO:0048714
GO:0048856
GO:0048870
GO:0051059
GO:0060766
GO:0060789
GO:0061029
GO:0061198
GO:0061629
GO:0070822
GO:0070888
GO:0090090
GO:0140096
GO:0140110
GO:0140297
GO:0160008
GO:0160009
GO:1902455
GO:1902459
GO:1990841
GO:2000736
GO:2001243
ILMN_2733514
Msa.9756.0_f_at
mMC021215
u80780_s_at
Participates
as an output of
SUMOylation of HDAC1 with SUMO1 (Mus musculus)
Other forms of this molecule
Hdac1 [nucleoplasm]
Inferred From
monoSUMO1-K444,K476-HDAC1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 444 (in Homo sapiens)
Coordinate
444
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 476 (in Homo sapiens)
Coordinate
476
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
NP_032254.1
ZINC - Investigational
HDAC1_MOUSE
ZINC - World Drugs
HDAC1_MOUSE
ZINC - FDA approved
HDAC1_MOUSE
ZINC - Substances
HDAC1_MOUSE
ZINC target
O09106
Ensembl
ENSMUSG00000028800
,
ENSMUSP00000099657
,
ENSMUST00000102597
ZINC - Biogenic
HDAC1_MOUSE
PRO
O09106
MGI
108086
ZINC - Predictions - Purchasable
HDAC1_MOUSE
Interactors (19)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q60520 Sin3a
3
Sin3a [nucleoplasm]
(R-MMU-4086071)
Sin3a [nucleoplasm]
(R-MMU-573326)
Sin3a [nucleoplasm]
(R-MMU-351657)
0.773
9
UniProt:Q6ZQ88
1
KDM1A [nucleoplasm]
(R-MMU-996769)
0.723
7
UniProt:Q9R190 Mta2
1
Mta2 [nucleoplasm]
(R-MMU-5096453)
0.708
7
UniProt:P70288 Hdac2
2
monoSUMO1-K462-HDAC2 [nucleoplasm]
(R-MMU-4615958)
Hdac2 [nucleoplasm]
(R-MMU-573366)
0.643
5
UniProt:O88939 ZBT7A
0.641
3
UniProt:Q8VI24 Satb2
2
Satb2 [nucleoplasm]
(R-MMU-4615865)
Satb2 [nucleoplasm]
(R-MMU-8985276)
0.564
4
UniProt:P22091 Tal1
2
Tal1 [nucleoplasm]
(R-MMU-9616213)
Tal1 [nucleoplasm]
(R-MMU-8956511)
0.564
3
UniProt:P20263 Pou5f1
2
Pou5f1 [nucleoplasm]
(R-MMU-3245981)
POU5F1 [nucleoplasm]
(R-MMU-452472)
0.527
4
UniProt:Q8CFE3
1
Rcor1 [nucleoplasm]
(R-MMU-996766)
0.527
2
UniProt:Q61188 Ezh2
1
Ezh2 [nucleoplasm]
(R-MMU-5617899)
0.527
5
UniProt:E9QAG8
17
Znf431 [nucleoplasm]
(R-MMU-9843457-20)
Znf431 [nucleoplasm]
(R-MMU-9843461-20)
Znf431 [nucleoplasm]
(R-MMU-9843524-20)
Znf431 [nucleoplasm]
(R-MMU-2586613-20)
Znf431 [nucleoplasm]
(R-MMU-1027421-20)
Znf431 [nucleoplasm]
(R-MMU-1247531-20)
Znf431 [nucleoplasm]
(R-MMU-1247542-20)
Znf431 [nucleoplasm]
(R-MMU-2127573-20)
Znf431 [nucleoplasm]
(R-MMU-2127569-20)
Znf431 [nucleoplasm]
(R-MMU-3323094-20)
Znf431 [nucleoplasm]
(R-MMU-2127597-20)
Znf431 [nucleoplasm]
(R-MMU-975011-20)
Znf431 [nucleoplasm]
(R-MMU-975012-20)
Znf431 [nucleoplasm]
(R-MMU-1973899-20)
Znf431 [nucleoplasm]
(R-MMU-1247871-20)
Znf431 [nucleoplasm]
(R-MMU-1247857-20)
Znf431 [nucleoplasm]
(R-MMU-2454142-20)
0.524
3
UniProt:Q02591 Gsc
1
Gsc [nucleoplasm]
(R-MMU-9756949)
0.524
2
UniProt:P13864 Dnmt1
3
monoSUMO1-K-DNMT1 [nucleoplasm]
(R-MMU-4655353)
Dnmt1 [nucleoplasm]
(R-MMU-573310)
DNMT1 [nucleoplasm]
(R-MMU-212181)
0.524
3
UniProt:Q04207
7
Rela [nucleoplasm]
(R-MMU-8865233)
phospho-Rela [nucleoplasm]
(R-MMU-9861499)
phospho-Rela [nucleoplasm]
(R-MMU-5660642)
Rela [nucleoplasm]
(R-MMU-177676)
Rela [cytosol]
(R-MMU-168172)
Rela [nucleoplasm]
(R-MMU-4755466)
phospho-Rela [nucleoplasm]
(R-MMU-5624468)
0.499
2
UniProt:P53566 Cebpa
2
Cebpa [nucleoplasm]
(R-MMU-381289)
Cebpa [nucleoplasm]
(R-MMU-442502)
0.499
2
UniProt:P25799
8
Nfkb1 [specific granule lumen]
(R-MMU-6799557)
Nfkb1 [extracellular region]
(R-MMU-6806304)
Nfkb1 [secretory granule lumen]
(R-MMU-6801004)
phospho-Nfkb1 [cytosol]
(R-MMU-451619)
phospho-Nfkb1 [cytosol]
(R-MMU-451611)
Nfkb1 [cytosol]
(R-MMU-451607)
Nfkb1 [nucleoplasm]
(R-MMU-177655)
Nfkb1 [cytosol]
(R-MMU-168168)
0.499
2
UniProt:O54864
1
SUV39H1 [nucleoplasm]
(R-MMU-427517)
0.462
2
UniProt:Q60I23 Q60I23
0.462
2
UniProt:P48432 Sox2
2
Sox2 [nucleoplasm]
(R-MMU-3246072)
Sox2 [nucleoplasm]
(R-MMU-452271)
0.462
2
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