Reactome | Mbd3 [nucleoplasm]

Mbd3 [nucleoplasm]

Stable Identifier

R-MMU-4657010

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

MBD3, Q9Z2D8

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase I Transcription (Mus musculus)
  - RNA Polymerase I Promoter Clearance (Mus musculus)
    - RNA Polymerase I Transcription Initiation (Mus musculus)
      - Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Mus musculus)
        
        TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Mus musculus)
        
        NuRD complex [nucleoplasm] (Mus musculus)
        
        Mbd3 [nucleoplasm] (Mus musculus)
- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - Regulation of TP53 Activity (Mus musculus)
        
        Regulation of TP53 Activity through Acetylation (Mus musculus)
        
        MTA2-NuRD complex deacetylates TP53 (Mus musculus)
        
        MTA2-NuRD complex [nucleoplasm] (Mus musculus)
        
        Mbd3 [nucleoplasm] (Mus musculus)

Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - PTEN Regulation (Mus musculus)
      - Regulation of PTEN gene transcription (Mus musculus)
        
        SALL4 recruits NuRD to PTEN gene (Mus musculus)
        
        NuRD complex [nucleoplasm] (Mus musculus)
        
        Mbd3 [nucleoplasm] (Mus musculus)
        
        SALL4:NuRD:PTEN gene [nucleoplasm] (Mus musculus)
        
        SALL4:NuRD [nucleoplasm] (Mus musculus)
        
        NuRD complex [nucleoplasm] (Mus musculus)
        
        Mbd3 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9Z2D8 Mbd3

Gene Names

Mbd3

Chain

chain:1-285

Reference Genes

BioGPS Gene:17192 Mbd3

ENSEMBL:ENSMUSG00000035478.15 Mbd3

KEGG Gene (Mus musculus):17192 Mbd3

Monarch:17192 Mbd3

NCBI Gene:17192 Mbd3

UCSC:Q9Z2D8 Mbd3

Reference Transcript

Other Identifiers

101385_at

10370824

1417728_at

17192

17242910

4411079

4424272

4614465

4658009

4707588

4947024

5042788

5098731

5262418

5283792

5475357

A_51_P398004

A_55_P1960873

A_55_P2739628

A_66_P127024

GE36686

GO:0000122

GO:0000785

GO:0000792

GO:0001701

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006325

GO:0006338

GO:0006346

GO:0006351

GO:0006355

GO:0007507

GO:0008327

GO:0009888

GO:0014070

GO:0016581

GO:0030154

GO:0031667

GO:0032355

GO:0032991

GO:0042659

GO:0043226

GO:0044030

GO:0045892

GO:0045893

GO:0048568

GO:0048856

GO:2000736

ILMN_2730498

aa242328_at

aa242328_g_at

mMC010245

Participates

as a component of

Other forms of this molecule

Mbd3 [nucleoplasm]

Inferred From

MBD3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_038623.1, NP_001293072.1

Ensembl

ENSMUSP00000100986, ENSMUST00000092295, ENSMUSP00000089948, ENSMUST00000105349, ENSMUSG00000035478

PRO

Q9Z2D8

MGI

1333812

HMDB Protein

HMDBP12761

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P14404 Mecom	1	Mecom [nucleoplasm] (R-MMU-9830485)	0.565	4