Reactome | monoSUMO1-K277,K309-IKBKG [nucleoplasm]

monoSUMO1-K277,K309-IKBKG [nucleoplasm]

Stable Identifier

R-MMU-4755449

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

O88522

Locations in the PathwayBrowser for interactor UniProt:P24772 PG200

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External Reference Information

External Reference

UniProt:O88522

Reference Genes

BioGPS Gene:16151

ENSEMBL:ENSMUSG00000004221

KEGG:mmu:16151

Monarch:16151

NCBI Gene:16151

UCSC:O88522

Reference Transcript

Other Identifiers

103216_f_at

10600453

106513_at

114642_at

1421209_s_at

1435646_at

1435647_at

1450161_at

1454690_at

16151

17535877

4313142

4351254

4361674

4377973

4536196

4656738

4666587

4683716

4696993

4744405

4776859

4811573

4901553

4916474

4973696

5001324

5120936

5124760

5171063

5186378

5195279

5211541

5228344

5452504

5454553

5488773

5500938

5582986

94196_at

AA198384_at

A_51_P260300

A_51_P380201

A_51_P423404

A_52_P156110

A_52_P507853

A_55_P2050652

GE35594

GO:0000151

GO:0000922

GO:0001782

GO:0002376

GO:0003824

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0006355

GO:0006974

GO:0007249

GO:0008385

GO:0010628

GO:0012501

GO:0016239

GO:0016301

GO:0016740

GO:0019904

GO:0031593

GO:0031625

GO:0032991

GO:0033209

GO:0035591

GO:0042742

GO:0042802

GO:0042803

GO:0042975

GO:0043123

GO:0043226

GO:0043276

GO:0044877

GO:0045944

GO:0046872

GO:0046982

GO:0050862

GO:0051092

GO:0051650

GO:0060090

GO:0065003

GO:0070530

GO:0072686

GO:0098542

GO:1902236

GO:1990450

GO:1990459

ILMN_1220188

ILMN_2598585

ILMN_2630423

ILMN_2698097

mMC003436

mMR030958

Participates

as an output of

PIAS4 SUMOylates IKBKG with SUMO1 (Mus musculus)

Other forms of this molecule

IKBKG [cytosol]

Ub-285-IKBKG [cytosol]

K63polyUb-IKBKG [cytosol]

IKBKG [nucleoplasm]

Inferred From

monoSUMO1-K277,K309-IKBKG [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 277 (in Homo sapiens)

Coordinate

277

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 309 (in Homo sapiens)

Coordinate

309

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

XP_006527915.1, XP_006527914.1, NP_001154895.1, XP_006527913.1, NP_034677.2, XP_011245829.1

ENSEMBL

ENSMUSP00000109762, ENSMUSP00000109763, ENSMUST00000114128, ENSMUSP00000126770, ENSMUST00000114127, ENSMUST00000164101, ENSMUST00000114133, ENSMUSP00000109768

PRO

O88522

MGI

1338074

PDB

2V4H, 3F89, 3JSV, 4OWF, 2ZVN, 2ZVO

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O88351	2	phospho-p-S177,S181-IKBKB [cytosol] (R-MMU-202506) IKBKB [cytosol] (R-MMU-168114)	0.896	8
UniProt:Q60680	4	phospho-p-Y187,Y198-CHUK [cytosol] (R-MMU-9861501) phospho-p-T23-CHUK [cytosol] (R-MMU-198615) phospho-p-S176,S180-CHUK [cytosol] (R-MMU-177667) CHUK [cytosol] (R-MMU-168104)	0.85	6
IntAct:EBI-4399559 UBIQ			0.71	5
UniProt:P62991 UBIQ			0.676	3
UniProt:Q924T7	1	RNF31 [cytosol] (R-MMU-5212660)	0.623	7
UniProt:O88522	5	IKBKG [cytosol] (R-MMU-168108) Ub-285-IKBKG [cytosol] (R-MMU-741397) K63polyUb-IKBKG [cytosol] (R-MMU-202530) IKBKG [nucleoplasm] (R-MMU-4755413) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-MMU-4755449)	0.592	2
UniProt:P24772 PG200			0.499	2