Reactome | Clock [cytosol]

Clock [cytosol]

Stable Identifier

R-MMU-508720

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Circadian locomoter output cycles protein kaput, CLOCK_MOUSE, Clock

External Reference Information

External Reference

UniProt:O08785 Clock

Gene Names

Clock

Chain

chain:1-855

Reference Genes

BioGPS Gene:12753 Clock

KEGG:mmu:12753 Clock

Monarch:12753 Clock

NCBI Gene:12753 Clock

UCSC:O08785 Clock

Reference Transcript

Other Identifiers

10338933

10343043

10343616

10530733

114107_at

115597_at

12753

1418659_at

1418660_at

1435775_at

1439314_at

17448960

4329196

4339916

4418854

4454430

4472503

4514404

4523211

4528685

4554708

4555937

4595622

4603142

4636138

4644820

4685248

4699154

4727899

4750084

4895849

4910043

4913022

5037319

5040020

5040595

5047243

5067246

5081703

5088589

5096249

5128111

5131828

5207083

5221138

5254529

5276747

5283175

5310949

5338367

5343649

5427196

5437283

5497684

5547966

5616320

92257_at

AF000998_at

AF000998_g_at

A_52_P161365

A_52_P279391

A_52_P334670

A_52_P334677

A_55_P2741789

A_55_P2746404

GE37022

GO:0000077

GO:0000978

GO:0000981

GO:0001228

GO:0003677

GO:0003700

GO:0003824

GO:0004402

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005694

GO:0005726

GO:0005737

GO:0005829

GO:0006325

GO:0006338

GO:0006355

GO:0006357

GO:0006473

GO:0006974

GO:0007283

GO:0007623

GO:0016740

GO:0016746

GO:0022414

GO:0030163

GO:0031490

GO:0032922

GO:0033391

GO:0042634

GO:0042752

GO:0042753

GO:0043161

GO:0043226

GO:0043231

GO:0043565

GO:0045892

GO:0045893

GO:0045944

GO:0046983

GO:0048511

GO:0050729

GO:0050796

GO:0051092

GO:0051775

GO:0061733

GO:0070888

GO:0071479

GO:0140096

GO:0140110

GO:1990513

GO:1990837

GO:2000074

GO:2000323

ILMN_2589603

ILMN_2600964

ILMN_2610973

mMC003808

mMC022282

mMR026549

Participates

as an output of

Expression of Clock (Mus musculus)

as a member of

Clock,Npas2 [cytosol] (Mus musculus)

Other forms of this molecule

p-S-Clock [nucleoplasm]

Cross References

RefSeq

NP_031741.1, XP_017176139.1, XP_017176137.1, NP_001276755.1

ENSEMBL

ENSMUST00000075159, ENSMUST00000202651, ENSMUSP00000074656, ENSMUSP00000143939

PRO

O08785

MGI

99698

GlyGen

O08785

PDB

4F3L, 8OSL, 5VJX, 8OSK, 5VJI, 8OSJ

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9WTL8 Arntl	4	Arntl [nucleoplasm] (R-MMU-9769624) Bmal1 [nucleoplasm] (R-MMU-9634872) Arntl [cytosol] (R-MMU-508660) p-S-Arntl [nucleoplasm] (R-MMU-508690)	0.974	39
UniProt:P97784 Cry1	4	ub-p-Cry1 [nucleoplasm] (R-MMU-517961) p-Cry1 [nucleoplasm] (R-MMU-508662) p-Cry1 [cytosol] (R-MMU-508644) Cry1 [cytosol] (R-MMU-508637)	0.85	10
UniProt:O54943 Per2	4	ub-p-Per2 [cytosol] (R-MMU-517951) p-Per2 [nucleoplasm] (R-MMU-508610) p-Per2 [cytosol] (R-MMU-508728) Per2 [cytosol] (R-MMU-508621)	0.783	10
UniProt:Q923E4 Sirt1	2	Sirt1 [nucleoplasm] (R-MMU-5211238) SIRT1 [nucleoplasm] (R-MMU-427531)	0.746	11
UniProt:Q9WTL8-4 BMAL1			0.646	10
IntAct:EBI-1808974 DBP			0.564	2
UniProt:P20444 Prkca	7	PRKCA [nucleoplasm] (R-MMU-450530) p-T497,T638,S657-Prkca [cytosol] (R-MMU-9010746) phospho-p-T497-PRKCA [cytosol] (R-MMU-5218731) phospho-p-T497,T638,S657-PRKCA [nucleoplasm] (R-MMU-5223292) phospho-pT497,T638,S657-PRKCA [plasma membrane] (R-MMU-4332340) PRKCA [plasma membrane] (R-MMU-156469) PRKCA [cytosol] (R-MMU-58196)	0.544	3
UniProt:Q14995 NR1D2	1	NR1D2 [nucleoplasm] (R-HSA-375501)	0.508	2
UniProt:Q14738 PPP2R5D	2	PPP2R5D [nucleoplasm] (R-HSA-3008956) PPP2R5D [cytosol] (R-HSA-3008950)	0.508	2
UniProt:P62140 PPP1CB	4	PPP1CB [cytosol] (R-HSA-163405) PPP1CB P49R [cytosol] (R-HSA-9660547) PPP1CB A56P [cytosol] (R-HSA-9660543) PPP1CB [nucleoplasm] (R-HSA-62003)	0.508	2
UniProt:P67870 CSNK2B	5	CSNK2B [cytosol] (R-HSA-201693) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [secretory granule lumen] (R-HSA-6801319) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290)	0.508	2
UniProt:P51449 RORC	1	RORC [nucleoplasm] (R-HSA-446177)	0.508	2
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.508	2
UniProt:P30154 PPP2R1B	2	PPP2R1B [nucleoplasm] (R-HSA-166000) PPP2R1B [cytosol] (R-HSA-165980)	0.508	2
UniProt:Q92753 RORB	1	RORB [nucleoplasm] (R-HSA-446171)	0.508	2
UniProt:Q9JMK2 Csnk1e	4	Csnk1e [nucleoplasm] (R-MMU-508745) Csnk1e [cytosol] (R-MMU-206029) CSNK1E [nucleoplasm] (R-MMU-421306) CSNK1E [cytosol] (R-MMU-205877)	0.508	2
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.508	2
UniProt:Q03164 KMT2A	6	KMT2A [cytosol] (R-HSA-9818584) KMT2A(2719-3969) [cytosol] (R-HSA-9818590) KMT2A(1-2718) [cytosol] (R-HSA-9818597) KMT2A [nucleoplasm] (R-HSA-1183223) KMT2A(1-2718) [nucleoplasm] (R-HSA-9818591) KMT2A(2719-3969) [nucleoplasm] (R-HSA-9818593)	0.499	3
UniProt:Q3U1J4	1	Ddb1 [nucleoplasm] (R-MMU-53489)	0.499	4
ChEBI:16864 ADP-RIBOSE			0.499	7

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