Reactome | K48polyUb-VDAC1 [mitochondrial outer membrane]

K48polyUb-VDAC1 [mitochondrial outer membrane]

Stable Identifier

R-MMU-5205624

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

mitochondrial outer membrane

Synonyms

Q60932

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q60932

Reference Genes

BioGPS Gene:22333

ENSEMBL:ENSMUSG00000020402

ENSEMBL:ENSMUSG00000020402.12

KEGG Gene (Mus musculus):22333

Monarch:22333

NCBI Gene:22333

UCSC:Q60932

Reference Transcript

RefSeq:NM_011694.5

Other Identifiers

10375941

1415998_at

1436992_x_at

1437192_x_at

1437947_x_at

17249440

22333

4642737

4691767

4934415

4966804

5200213

5217859

5267286

5350218

5359055

5405324

5505925

5558484

5587633

A_55_P1992445

GE36267

GO:0000166

GO:0001662

GO:0005215

GO:0005253

GO:0005515

GO:0005739

GO:0005741

GO:0005743

GO:0005757

GO:0005886

GO:0006086

GO:0006790

GO:0006811

GO:0006820

GO:0006851

GO:0006914

GO:0006915

GO:0007005

GO:0007268

GO:0007270

GO:0007612

GO:0008021

GO:0008289

GO:0008308

GO:0012501

GO:0015288

GO:0015485

GO:0016020

GO:0019901

GO:0023052

GO:0030154

GO:0030855

GO:0031210

GO:0031410

GO:0031966

GO:0032991

GO:0042645

GO:0042802

GO:0043066

GO:0043209

GO:0043226

GO:0043227

GO:0044325

GO:0044877

GO:0045121

GO:0046930

GO:0048787

GO:0048856

GO:0050877

GO:0055085

GO:0055086

GO:0097001

GO:0098656

GO:0098839

GO:0110099

GO:1901135

GO:1903146

GO:1905091

GO:2000378

ILMN_2475585

ILMN_2832808

Msa.3230.0_s_at

U30840_s_at

mMC023442

Participates

as an input of

p62 binds ubiquitinated mitochondrial substrates (Mus musculus)

as an output of

Parkin promotes the ubiquitination of mitochondrial substrates (Mus musculus)

as a component of

K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Mus musculus)

Other forms of this molecule

PolyUb-VDAC1 [mitochondrial outer membrane]

VDAC1 [mitochondrial outer membrane]

Inferred From

K48polyUb-VDAC1 [mitochondrial outer membrane] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (K48-linked polyubiquitin chain [cytosol]) at unknown position

Modification

K48-linked polyubiquitin chain [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_035824.1

Ensembl

ENSMUST00000020673, ENSMUSP00000099819, ENSMUSG00000020402, ENSMUST00000102758, ENSMUSP00000020673

PRO

Q60932

MGI

106919

PDB

4C69, 7KUH, 7TCV, 3EMN

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q4ACU6	1	Shank3 [cytosol] (R-MMU-6794277)	0.527	3